The discovery of antibiotics in the 20th Century revolutionized healthcare, adding an average of 20 years to everyone's life. However, the overuse and misuse of antibiotics have led to the rise of antibiotic-resistant bacteria, or superbugs, which could cause a health crisis worse than any we've experienced this century. By 2050, it's predicted that 10 million people will die every year from complications with superbugs. A world without antibiotics would be catastrophic, impacting our food chain and causing many to die younger than they do now. As students, it's important to understand the consequences of antibiotic misuse and to be cautious when taking antibiotics. By finishing the full course of antibiotics, we can prevent the development of antibiotic-resistant bacteria. Additionally, we should be aware of the need for new antibiotics and support efforts to fund research into finding them. Anticipating problems and taking action before they become global crises is key to protecting our health and future.

If you're looking for a field of study that is both fascinating and essential to our everyday lives, then look no further than Microbiology! Microbiology is the study of microscopic organisms such as bacteria, viruses, fungi, and algae. It is a field that has a significant impact on our health, food, environment, and much more. One of the most appealing aspects of Microbiology is that it has a direct impact on our daily lives. For example, microbiologists play a critical role in developing vaccines, antibiotics, and other treatments for infectious diseases. They also work to ensure the safety of our food supply by monitoring for harmful bacteria and other microorganisms. In terms of research and innovation, Microbiology is a field that is constantly evolving. There are always new discoveries being made, such as the recent development of CRISPR-Cas9 gene editing technology. Microbiology also has a rich history, with notable figures such as Louis Pasteur and Robert Koch making groundbreaking contributions to the field. At the undergraduate level, students can expect to take courses in areas such as microbial genetics, immunology, and virology. There are also opportunities for further specialization, such as studying environmental microbiology or medical microbiology. Real-life examples of exciting careers in Microbiology include working as a clinical microbiologist, a food microbiologist, or a research scientist. There are a range of potential future jobs and roles that this field of study might be directly helpful for, including working in public health, biotechnology, pharmaceuticals, and more. Notable employers in the field include the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), and pharmaceutical companies such as Pfizer and Merck. To succeed in Microbiology, students should have a strong interest in science and a natural curiosity about the world around them. They should also be detail-oriented, analytical, and have excellent problem-solving skills. Overall, studying Microbiology is an exciting and rewarding experience that has the potential to make a real difference in the world. So if you're interested in a field that combines cutting-edge research with practical applications, then Microbiology might just be the perfect fit for you!

Researchers have identified lipid differences in patients with alcohol-related liver disease that could lead to earlier detection and new treatments. Sphingomyelins were found to be significantly reduced in scarred liver tissue, potentially serving as a biomarker for ALD. Learn more about this breakthrough research and its implications for the diagnosis and treatment of ALD.

Have you ever wondered how diseases spread and how they can be controlled? Are you passionate about improving public health and saving lives? If so, a career in epidemiology might be just what you're looking for! Epidemiology is the study of the distribution and determinants of health and disease in populations. It involves investigating patterns and causes of diseases, developing and implementing interventions to prevent and control them, and evaluating the effectiveness of these interventions. Epidemiologists work in a variety of settings, including government agencies, hospitals, universities, research institutions, and non-profit organizations. As an epidemiologist, you could work on a range of public health issues, from infectious diseases like COVID-19 and Ebola to chronic diseases like cancer and heart disease. You could investigate outbreaks of foodborne illness, design and evaluate vaccination programs, or study the effects of environmental exposures on health. Your work could help to inform public policy, improve health outcomes, and save lives. Typical duties of an epidemiologist include designing and conducting studies, collecting and analyzing data, interpreting results, and communicating findings to stakeholders. Epidemiologists may specialize in specific areas such as infectious disease epidemiology, environmental epidemiology, or social epidemiology. Other related fields include biostatistics, health policy, and global health. To become an epidemiologist, you typically need a graduate degree in epidemiology or a related field such as public health or biostatistics. Popular undergraduate majors include biology, chemistry, mathematics, and statistics. Helpful personal attributes for epidemiologists include strong analytical skills, attention to detail, and the ability to communicate complex information to a variety of audiences. Job prospects for epidemiologists are strong, with employment projected to grow faster than average over the next decade. There are a variety of potential employers for epidemiologists, including government agencies such as the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), hospitals and healthcare systems, universities and research institutions, and non-profit organizations such as the Bill and Melinda Gates Foundation and Doctors Without Borders. Some notable epidemiologists include Dr. Anthony Fauci, Dr. Nancy Messonnier, and Dr. Michael Osterholm. If you're interested in a career in epidemiology, there are many exciting opportunities to explore. With your skills and knowledge, you could make a real difference in improving public health and saving lives.

Horseshoe crabs, a resilient species that has existed for over 450 million years, are facing heightened pressures due to the booming global demand for their blue blood. This blood is the only known natural source of amebocyte lysate, a clotting agent used to detect dangerous endotoxins in a variety of human medical products, including COVID vaccines. The Atlantic horseshoe crab, already considered vulnerable by conservation groups, is facing dwindling numbers due to increased bleedings by biomedical companies. As the industry shifts towards the Atlantic species, questions arise about our obligations to the animals that supply life-saving materials for human benefit.

Vaccines are likely the most important public health intervention of the last 100 years, having saved over a billion lives. They have led to a massive reduction in child mortality in sub-Saharan Africa and can even prevent cancer. A world without vaccines would be unimaginable, with outbreaks of disease regularly all over the world. Vaccines are the only public health intervention that can bring equality, as they protect not only oneself but also one's family and community. While anti-vaccination fears have been around for over a century, it's important to engage with people where they are and understand their context, concerns, and experiences with health and vaccines. Taking a vaccine is not just a personal choice, but a moral choice that affects other people. Vaccines are fundamental to the privileges we have in the modern world and make it a safe place for most of us to be.

The immune system is a crucial part of our body's interconnected system, and a healthy gut microbiome is critical to a healthy immune system. Rather than trying to boost our immune system, we should focus on supporting it through a healthy lifestyle, including regular exercise, a diverse diet with plenty of fiber and polyphenols, stress reduction, and good sleep. While there is no magic pill to boost our immune response, scientists are constantly developing new drug treatments and therapies to combat a wide range of diseases. It is also important to note that risky procedures such as faecal transplants should only be done within the confines of a medical clinic. By understanding how our immune system works, we can take steps to keep it healthy and help win the war against infection.

New research has identified gold-based compounds that could treat multidrug-resistant "superbugs", with some effectiveness against several bacteria. Antibiotic resistance is a global public health threat, and the development of new antibiotics has stalled. Gold metalloantibiotics, compounds with a gold ion at their core, could be a promising new approach. Dr. Sara M. Soto Gonzalez and colleagues studied the activity of 19 gold complexes against a range of multidrug-resistant bacteria isolated from patients. The gold compounds were effective against at least one bacterial species studied, with some displaying potent activity against several multidrug-resistant bacteria.

Discover the secret behind Gram-negative bacteria's armor-like outer membrane! A new study led by Professor Colin Kleanthous at the University of Oxford sheds light on how bacteria like E. coli construct their outer membrane to resemble body armor, with implications for developing antibiotics.

Do you have a passion for helping others and a fascination with the human eye? If so, a career in optometry could be the perfect fit for you! Optometrists are healthcare professionals who specialize in diagnosing and treating vision problems and eye diseases. They play a vital role in helping people maintain healthy eyes and clear vision. As an optometrist, you'll have the opportunity to work with patients of all ages, from children to seniors. You'll use state-of-the-art technology to examine patients' eyes and diagnose problems such as nearsightedness, farsightedness, and astigmatism. You'll also be able to detect and treat eye diseases such as glaucoma, cataracts, and macular degeneration. One of the most appealing aspects of a career in optometry is the ability to make a real difference in people's lives. Imagine helping a child see clearly for the first time or saving someone's vision by detecting a serious eye disease early on. Optometrists have the power to improve their patients' quality of life in meaningful ways. In addition to traditional optometry, there are many areas of specialization within the field. Some optometrists choose to focus on pediatric optometry, working with children to ensure they have healthy eyes and clear vision. Others specialize in contact lenses, helping patients find the perfect lenses to fit their unique needs. And still others focus on low vision, working with patients who have severe visual impairments to help them navigate the world around them. To become an optometrist, you'll need to complete a Doctor of Optometry (OD) degree from an accredited optometry school. Popular undergraduate majors for aspiring optometrists include biology, chemistry, and physics. In addition to completing a rigorous academic program, you'll also need to pass a national board exam to become licensed to practice. Helpful personal attributes for a career in optometry include strong communication skills, attention to detail, and a passion for helping others. You'll also need to be comfortable using technology and working with a wide range of patients. Job prospects for optometrists are strong, with a projected growth rate of 10% over the next decade. Optometrists can work in a variety of settings, from private practices to hospitals to retail stores. Some notable employers in the field include LensCrafters, Kaiser Permanente, and the U.S. Department of Veterans Affairs. So if you're looking for a career that combines cutting-edge technology, meaningful patient interactions, and the opportunity to make a real difference in people's lives, consider a career in optometry!

Discover how human evolution has led to unique diseases like knee osteoarthritis, affecting millions worldwide. Professor Terence D. Capellini shares genetic research on the link between bipedalism and knee osteoarthritis, and how identifying high-risk patients at an early age can inform future therapies. Explore the Developmental and Evolutionary Genetics Lab's work and hypotheses published in his 2020 paper "Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk." Join the Harvard Museums of Science & Culture's ongoing series to learn more.

Frances Oldham Kelsey was a scientist who saved thousands of lives by rejecting an application to sell a drug called thalidomide. The drug was widely used in dozens of countries to treat insomnia, workplace stress, and nausea in pregnant women. However, Kelsey found the data on thalidomide's absorption and toxicity inadequate and rejected the application. Her earlier animal-based research demonstrated that drugs could pass from mother to fetus through the placenta, and she believed that thalidomide could cause harm to fetuses. Her decision to reject the application and ask for better evidence saved countless babies from severe birth defects caused by thalidomide. Kelsey's legacy endures as she prioritized facts over opinions and patience over shortcuts, making evidence-based medicine the foundation of reforms that continue to protect people today. By learning about Kelsey's story, students can understand the importance of evidence-based research and the impact of their decisions in science and medicine.

Stanford University researchers, in collaboration with other institutions, have developed a molecule that prevents the spike protein of the SARS-CoV-2 virus from twisting and infecting cells, including those with new variants. This new type of antiviral therapeutic, called the longHR2\_42 inhibitor, may be delivered via inhaler to treat early infections and prevent severe illness. The team's detailed understanding of the twisted structure of the virus's spike protein allowed them to create a longer molecule that is more effective than previous attempts to block the virus. Their groundbreaking research may lead to a promising solution to combat COVID-19.

Are you interested in learning about the dangers of antimicrobial resistance and why it's such a big deal? Look no further than the World Health Organization's reference article on the topic! This informative piece explains how antimicrobial resistance occurs and why it's such a threat to our health and the health of our planet. You'll learn about the various factors driving antimicrobial resistance, as well as the impact it can have on medical procedures and the global economy. Don't miss out on this important read!

Organ transplants are a life-saving medical breakthrough that have revolutionized the field of medicine. Kidneys are essential organs that filter waste material from the blood and process it into urine. A typical dialysis patient has a poorer life expectancy than many cancers. Removing one kidney should not affect someone's lifespan or quality of life. A kidney from a living donor in general will have a much better quality because it comes from a healthy and tested person. Kidneys are expected to survive up to twice as long on average in the recipient. Currently, it's not allowed to donate a kidney under any form of payment. However, incentivizing people to donate more is actually a way to starve black markets. It's not to recreate them, it's to undermine them. If you reward a person amply for the sacrifice they've made, something they go into with their eyes open and well informed, that's not exploitation. Organ donation is an incredible gift that can save someone's life so palpably, and everyone should consider donating.

Mitochondria are often referred to as the powerhouses of the cell and for good reason. These tiny organelles are responsible for producing the energy that our cells need to function. In this write-up, we'll explore the magic of mitochondria and why they are so important to our health and well-being. Did you know that mitochondria are sometimes referred to as the "second genome"? This is because they have their own DNA and can replicate independently of the cell's nucleus. This discovery, made by Dr. Douglas C. Wallace in the late 1970s, revolutionized our understanding of cellular biology. Another interesting fact about mitochondria is that they are thought to have originated from a symbiotic relationship between early cells and primitive bacteria. Over time, the two organisms evolved together to form the cells that make up our bodies today. This theory, known as the endosymbiotic theory, was first proposed by Dr. Lynn Margulis in the 1960s. So, what exactly do mitochondria do? Well, they are responsible for producing energy in the form of ATP (adenosine triphosphate) through a process called cellular respiration. This energy is then used by our cells to carry out all of their functions, from moving and growing, to repairing and reproducing. It's important to note that our cells can't survive without energy, and without mitochondria, we wouldn't be able to produce enough energy to support our bodies. This is why mitochondria are so critical to our health and well-being. By learning more about the magic of mitochondria, you'll gain a deeper understanding of cellular biology and the role that these tiny organelles play in our lives. So, get reading, reflecting, and exploring!

Have you ever wondered what it takes to be a heart doctor? Well, look no further because we've got the inside scoop on the exciting and rewarding field of cardiology! As a cardiologist, you'll be responsible for diagnosing and treating heart conditions, helping patients live longer, healthier lives. From heart attacks to arrhythmias, you'll have the knowledge and skills to provide life-saving care to those in need. But being a cardiologist isn't just about saving lives, it's also about preventing heart disease. You'll work with patients to develop healthy habits and manage risk factors, like high blood pressure and high cholesterol. And the best part? The field of cardiology is constantly evolving, with new treatments and technologies being developed all the time. You'll have the opportunity to stay at the forefront of medical advancements and make a real difference in the lives of your patients. Typical duties of a cardiologist include performing diagnostic tests, like electrocardiograms and echocardiograms, prescribing medication and lifestyle changes, and performing procedures like angioplasty and stenting. There are also many areas of specialisation within the field, such as electrophysiology and interventional cardiology. To become a cardiologist, you'll need to complete extensive education and training. This typically includes a bachelor's degree in a relevant field, such as biology or chemistry, followed by medical school and a residency in internal medicine. After that, you'll complete a fellowship in cardiology, where you'll gain specialised knowledge and skills. Helpful personal attributes for a career in cardiology include strong communication skills, attention to detail, and a passion for helping others. You'll also need to be able to work well under pressure and make quick decisions in life-or-death situations. Job prospects for cardiologists are excellent, with a growing demand for heart specialists around the world. Some notable potential employers include the Mayo Clinic, Cleveland Clinic, and Johns Hopkins Hospital, among many others. So, if you're looking for a challenging and rewarding career that allows you to make a real difference in the lives of others, consider becoming a cardiologist. Your heart (and your patients' hearts) will thank you!

Are you curious about the tiny viruses that inhabit your body? MIT Technology Review's biotech newsletter, The Checkup, explores the world of bacteriophages, or "phages" for short. These microscopic viruses have the potential to treat bacterial infections, but they've been largely abandoned in favor of antibiotics. With antimicrobial resistance on the rise, interest in phage therapy is making a comeback. Learn about the diversity and specificity of phages, and how they could be engineered to target specific bacteria. Discover the potential of phage therapy and the challenges that need to be overcome in this fascinating article.

Are you fascinated by the human body and how it works? Do you dream of becoming a doctor and making a difference in people's lives? Then pre-medicine might be the perfect field of study for you! Pre-medicine is a challenging and rewarding field that prepares students for medical school and a career in healthcare. It encompasses a wide range of subjects, from biology and chemistry to anatomy and physiology. Through this field of study, you will gain a deep understanding of the human body and the diseases that affect it. Research in pre-medicine is constantly evolving, with new innovations and breakthroughs being made all the time. For example, recent studies have shown that stem cell therapy may be a promising treatment for a variety of conditions, from heart disease to Parkinson's. Additionally, academic figures like Dr. Anthony Fauci have made significant contributions to the field, particularly in the area of infectious diseases. At the undergraduate level, typical majors and modules include biology, chemistry, and biochemistry. These foundational courses provide a strong basis for further specialization in areas such as neuroscience, pharmacology, or genetics. For example, you could become a specialist in neurology and work with patients who have disorders like Alzheimer's or Parkinson's. The potential career paths for pre-med graduates are vast and varied. Many go on to become doctors, working in fields such as pediatrics, cardiology, or oncology. Others pursue careers in related fields, such as medical research or public health. Notable employers include world-renowned hospitals such as the Mayo Clinic and Johns Hopkins, as well as organizations like the World Health Organization and Doctors Without Borders. To succeed in pre-medicine, it's important to have a strong work ethic, a passion for learning, and excellent communication skills. You should also have a keen interest in science and a desire to make a difference in people's lives. In conclusion, pre-medicine is an exciting and challenging field of study that offers a wealth of opportunities for those who are passionate about healthcare. With a strong foundation in biology and chemistry, you can specialize in a variety of areas and pursue a rewarding career in medicine or related fields. So if you're ready to make a difference in the world, consider studying pre-medicine and joining the ranks of healthcare professionals who are changing lives every day.

Did you know that air pollution can impair our sense of smell and cause anosmia? Studies have shown that exposure to small airborne pollution particles, largely from the combustion of fuels in vehicles, power stations and our homes, can lead to olfactory dysfunction, causing a gradual erosion of our sense of smell over time. This can have significant effects on our overall wellbeing, from reducing our ability to taste and enjoy food, to potentially being an early warning sign of dementia. Researchers from Johns Hopkins School of Medicine and Karolinska Institute have found a strong correlation between higher pollution levels and poorer smelling ability, suggesting that we need to take air pollution more seriously to protect our health.