Cancer is a disease that affects millions of people worldwide and has been a subject of intense research for decades. Thanks to recent advances in cancer treatment, survival rates are on the rise, and more and more people are able to beat the disease. One of the key developments in cancer treatment has been the use of immunotherapy. This approach harnesses the power of the patient's own immune system to fight cancer cells. For example, the drug Keytruda, which was developed by three developers -- Hans van Eenennaam, John Dulos and Andrea van Elsas -- has been shown to be effective in treating several types of cancer, including melanoma and non-small cell lung cancer. Another exciting development in cancer treatment is the use of precision medicine. This approach uses genetic information to tailor treatments to individual patients, increasing their effectiveness and reducing side effects. For example, the drug Gleevec, which was developed by Dr. Brian Druker, has revolutionized the treatment of certain types of cancer (such as acute lymphoblastic leukaemia, chronic myeloid leukaemia, gastrointestinal stromal tumours, and myelodysplastic/myeloproliferative diseases), leading to high cure rates in patients with this disease. Additionally, advances in radiation therapy have also played a major role in the fight against cancer. Today, more precise and targeted radiation treatments are available, reducing side effects and improving outcomes for patients. For example, proton therapy, which was developed by Elekta, uses beams of protons to precisely target cancer cells, minimizing damage to healthy tissue.

A groundbreaking study from Weill Cornell Medicine has identified four distinct subtypes of autism based on brain activity and behavior. Machine learning was used to analyze neuroimaging data from 299 people with autism and 907 neurotypical individuals, revealing patterns of brain connections linked to behavioral traits. The study shows promise for personalized therapies and new approaches to diagnosis and treatment.

Get ready to revolutionize the way we treat cancer and age-related diseases! A new company, GlioQuell, co-founded by Dr. Kambiz Alavian from the Department of Brain Sciences, is developing a cutting-edge approach to target the powerhouses of cancer cells - the mitochondria. By reducing the efficiency of these structures, GlioQuell aims to turn off the cancer cells' energy supply and treat one of the most aggressive forms of cancer - glioblastoma.

Artificial Intelligence (AI) is transforming the healthcare industry in ways we never imagined. AI has the potential to revolutionize the way we diagnose, treat, and prevent diseases. With the help of AI, medical professionals can now analyze large amounts of data in seconds, making the process of diagnosing and treating patients much more efficient. Leading academics such as Dr. Eric Topol, a cardiologist and digital health pioneer, have been working on incorporating AI into healthcare for years. For example, Dr. Topol has been working on developing AI algorithms that can help diagnose diseases from scans and images, reducing the need for invasive procedures. He has also been studying the use of AI in personalized medicine, where AI can help predict the best treatment for a patient based on their specific genetic makeup. Statistics show that AI is already having a positive impact on healthcare. In 2019, researchers used AI to diagnose skin cancer with accuracy comparable to human dermatologists. Another study found that AI could help detect breast cancer up to five years before a traditional mammogram. These are just a few examples of how AI is changing the face of healthcare. AI is also helping healthcare professionals work more efficiently. For example, AI algorithms can quickly analyze medical records and help doctors identify patients who need immediate attention. This saves time and reduces the risk of missing critical information.

Do you have a passion for science and a desire to help people? If so, Optometry may be the perfect field of study for you. Optometry is a branch of medicine that focuses on the eyes and vision. It is a fascinating field that combines science, technology, and patient care to help people see clearly and live their best lives. Optometry is all about helping people to see the world around them. As an optometrist, you will use your knowledge of the eyes and vision to diagnose and treat a range of eye conditions, from simple refractive errors to more complex diseases such as glaucoma and cataracts. You will also help people to maintain their eye health and prevent vision problems from developing. One of the most exciting aspects of Optometry is the constant innovation and research that is taking place in the field. From new technologies that allow for more accurate diagnosis and treatment, to groundbreaking research into the causes and treatments of eye diseases, there is always something new and exciting happening in Optometry. At the undergraduate level, typical majors and modules include anatomy and physiology of the eye, optics, visual perception, and ocular disease. Students will also have the opportunity to gain practical experience through clinical placements and internships. After completing their undergraduate degree, students can go on to specialize in areas such as pediatric optometry, contact lenses, or vision therapy. With a degree in Optometry, there are a range of potential job opportunities available. Optometrists can work in private practice, hospitals, clinics, or for government agencies. Some notable employers in the field include Bausch + Lomb, Johnson & Johnson, and Essilor. To succeed in Optometry, students should have a strong background in science, particularly biology and chemistry. They should also possess excellent communication and interpersonal skills, as they will be working closely with patients on a daily basis. If you are passionate about science and helping people, a degree in Optometry may be the perfect choice for you.

Discover how human evolution has led to unique diseases like knee osteoarthritis, affecting millions worldwide. Professor Terence D. Capellini shares genetic research on the link between bipedalism and knee osteoarthritis, and how identifying high-risk patients at an early age can inform future therapies. Explore the Developmental and Evolutionary Genetics Lab's work and hypotheses published in his 2020 paper "Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk." Join the Harvard Museums of Science & Culture's ongoing series to learn more.

Did you know that adults catch more than 150 colds throughout their lives, and that a single family of viruses causes 30 to 50% of all colds? Understanding the complex relationship between viruses and our immune systems is not only fascinating, but also highly relevant to our daily lives. By reading about pleconaril, rhinovirus, and CRISPR, you'll learn about the science behind vaccines and antiviral drugs, and how they could help us tackle the common cold. But beyond that, exploring this topic will help you appreciate the incredible complexity and resilience of our immune systems, and the importance of maintaining our health. So grab a cup of tea and your favorite notebook, and get ready to dive into the fascinating world of viruses and immune systems!

Unlock the secrets of Alzheimer's disease with single-cell profiling! MIT scientists have made rapid progress in understanding Alzheimer's disease by using single-cell profiling technologies. By analyzing genetic activity in individual cells, they have identified five main areas of cellular function, or "pathways," that are disrupted in the disease. These findings hold strong potential for explaining the disease and developing meaningful therapies.

Cancer is one of the leading causes of death worldwide and has been the focus of countless scientific studies and research projects. In the field of biochemistry, scientists have made tremendous progress in understanding the underlying mechanisms of cancer and developing new treatments to fight it. One of the most exciting breakthroughs in the field of cancer research has been the discovery of targeted therapies. These treatments are designed to specifically target the genetic mutations that cause cancer, rather than simply killing all rapidly dividing cells, which can lead to side effects. For example, imatinib (brand name Gleevec) is a targeted therapy that was developed to treat chronic myeloid leukemia (CML), and has been incredibly successful in treating this form of cancer. Another area of biochemistry that is making a big impact in the fight against cancer is the study of cancer metabolism. Researchers have found that cancer cells have a unique metabolism that allows them to rapidly divide and grow. By targeting this unique metabolism, scientists are developing new treatments that can specifically target cancer cells, while leaving healthy cells unharmed. One of the leading scientists in the field of cancer metabolism is Dr. Lewis Cantley, a Professor of Cancer Biology at Weill Cornell Medicine. He has made numerous contributions to the field, including the discovery of the PI3K pathway, which is a key player in cancer cell metabolism. By targeting this pathway, scientists are developing new treatments that can effectively fight cancer. So, whether you're a student who is just starting to learn about biochemistry and cancer research, or you're an experienced researcher looking to make an impact in this field, there are countless exciting opportunities to get involved and make a difference. The battle against cancer is a journey through biochemistry that is waiting for you to join!

Are you fascinated by the human body and its inner workings? Do you have a passion for helping others and making a meaningful impact on people's lives? Then a career in Medicine might be just what you're looking for! Medicine is a field of study that encompasses everything from the smallest cells to the largest organ systems, with a focus on understanding and treating diseases and injuries. It's a challenging and rewarding career that requires a lot of hard work and dedication, but the potential rewards are enormous. Some of the most exciting developments in Medicine today are in the areas of genomics, personalized medicine, and regenerative medicine. Researchers are exploring new ways to use genetics to diagnose and treat diseases, while also developing new treatments that can regenerate damaged tissues and organs. One of the many inspiring figures in Medicine is Dr. Paul Farmer, who has dedicated his life to providing healthcare to some of the world's poorest communities. He founded Partners in Health, an organization that has helped to bring lifesaving medical care to millions of people around the world. At the undergraduate level, students typically study a range of subjects including anatomy, physiology, pharmacology, and pathology. They also gain practical experience through clinical rotations and internships. Some students may choose to specialize in areas such as surgery, pediatrics, or oncology. There are many potential career paths for those who study Medicine, including roles as physicians, surgeons, researchers, and healthcare administrators. Some of the most notable employers in this field include the World Health Organization, Doctors Without Borders, and the Mayo Clinic. To succeed in Medicine, it's important to have a strong foundation in science and math, as well as excellent communication and problem-solving skills. A genuine passion for helping others and a commitment to lifelong learning are also essential. If you're ready to embark on an exciting and rewarding career in Medicine, there's no better time to start exploring your options!

As we grow older, our bodies undergo many changes, including changes in our metabolism. Metabolism refers to the chemical processes that occur in our bodies to maintain life. These processes are essential for providing energy, building and repairing tissues, and eliminating waste products. As we age, our metabolic pathways can become altered, leading to various age-related diseases and conditions. One example of a metabolic pathway that is affected by aging is the mitochondrial electron transport chain (ETC). The ETC is responsible for producing ATP, the primary source of energy for our cells. As we age, the function of the ETC can become impaired, leading to a decrease in ATP production and an increase in oxidative stress. This can contribute to age-related diseases such as Alzheimer's disease, Parkinson's disease, and diabetes. Another example is the mTOR (mechanistic target of rapamycin) pathway, which regulates cellular growth and metabolism. Studies have shown that inhibiting the mTOR pathway can increase lifespan in various model organisms, including mice. This has led to increased interest in developing drugs that target this pathway as a potential anti-aging strategy. One of the leading academics in this field is Dr. David Sinclair, a Professor of Genetics at Harvard Medical School. Dr. Sinclair's research has focused on the role of metabolism in aging and age-related diseases, and he has made significant contributions to the field. For example, his research has shown that supplementing with NAD+, a molecule involved in energy metabolism, can improve various aspects of aging in mice. Another leading academic in this field is Dr. Valter Longo, a Professor of Gerontology and Biological Science at the University of Southern California. Dr. Longo's research has focused on the role of fasting and caloric restriction in aging and age-related diseases. His work has shown that periodic fasting can have a range of health benefits, including improving insulin sensitivity and reducing inflammation. In conclusion, the study of metabolic pathways in aging is a fascinating and rapidly growing field. By understanding the complex interplay between metabolism and aging, we can better understand the underlying causes of age-related diseases and conditions. Students who are interested in this topic can continue to explore it through reading and research, or by pursuing their own experiments and projects. With the right tools and resources, they can make meaningful contributions to this exciting field and help improve our understanding of aging and metabolic pathways.

Medical research is a fascinating field of study that explores the complexities of the human body and its many diseases. It's an exciting area of research that is constantly evolving, with new discoveries and innovations being made every day. One of the most appealing aspects of medical research is the potential to make a real difference in people's lives. Researchers in this field are at the forefront of developing new treatments and therapies for a wide range of illnesses, from cancer to Alzheimer's disease. One example of groundbreaking research in this field is the development of immunotherapy, a treatment that harnesses the power of the immune system to fight cancer. This innovative approach has already helped to save countless lives and is just one example of the many exciting breakthroughs being made in medical research. At the undergraduate level, students can expect to take a variety of modules that cover topics such as genetics, molecular biology, and epidemiology. These modules provide a solid foundation in the basic principles of medical research and prepare students for further specialisation in areas such as cancer research or infectious diseases. Potential future jobs and roles in medical research include positions as research scientists, clinical trial coordinators, and medical writers. There are also many opportunities to work in public health or in the pharmaceutical industry, with notable employers including the National Institutes of Health, Pfizer, and GlaxoSmithKline. To succeed in this field of study, students should have a strong interest in science and a passion for helping others. They should also possess excellent analytical and critical thinking skills, as well as the ability to work independently and as part of a team. Overall, the study of medical research is an exciting and rewarding field that offers endless possibilities for those who are passionate about making a difference in the world of healthcare.

Weight loss surgery decreases bile acids linked to higher appetite, but lifestyle changes could mimic the effect. Researchers from King's, the University of Nottingham, and Amsterdam University Medical Centre found that gut microbes play a key role in regulating bile acids and metabolism. The study's results have important implications for targeted interventions for metabolic disorders focused on the gut microbiome. Co-author Professor Tim Spector, the co-founder of personalised nutrition company ZOE, highlights the promise of gut microbiome testing in supporting metabolic health.

Scientists have developed a groundbreaking treatment for blood cancer using off-the-shelf T-cells. The CALM clinical trial evaluated the potential of UCART19, an "off-the-shelf" CAR-T cell product, against adult patients with B-ALL. The results were recently published in The Lancet Haematology and Cancer Research Communications, showing that 48% of treated patients achieved complete remission lasting an average of 7.4 months. This new approach offers a more efficient and effective alternative to traditional CAR-T cell therapy, providing hope for patients with relapsed or treatment-resistant blood cancers.

Did you know that every time you visit the doctor or take a medication, you are contributing to the vast amounts of health data that are collected and analyzed? Thanks to advances in technology and the rise of big data, these massive amounts of information are now being used to revolutionize the field of medicine, and the results are nothing short of incredible. Data-driven medicine is the practice of using vast amounts of health-related data to improve patient outcomes and healthcare delivery. By analyzing large amounts of patient information, healthcare providers can identify patterns and trends that would be impossible to detect otherwise. This information can be used to develop personalized treatment plans, predict disease outbreaks, and even prevent illnesses before they occur. One area where data-driven medicine has already made a significant impact is in cancer treatment. Thanks to the analysis of genetic data, doctors can now tailor treatments to individual patients based on their specific genetic profile, resulting in better outcomes and fewer side effects. In fact, the use of data-driven medicine in cancer treatment has already led to a 30% reduction in mortality rates. But data-driven medicine isn't just about treating disease. It's also about preventing it. By analyzing patient data, healthcare providers can identify risk factors for certain diseases and take steps to prevent them from developing. For example, doctors can use patient data to identify individuals who are at high risk for heart disease and develop personalized prevention plans that include exercise, diet changes, and medication. Leading academics in the field of data-driven medicine include Dr. Atul Butte, a professor of pediatrics and biomedical informatics at Stanford University, and Dr. Eric Topol, a professor of molecular medicine and the executive vice-president of Scripps Research. Both researchers have made significant contributions to the field, including the development of innovative data-driven tools and techniques that are transforming the way we approach healthcare. Remember, the key to success in exploring academic topics is to be curious, ask questions, and be willing to learn. With data-driven medicine, the possibilities are endless, and the potential to make a real difference in people's lives is huge.

We all know how important it is to stay healthy and avoid getting sick. But have you ever wondered about the science behind vaccines? In this video clip, we learn about the key academic concept of how the immune system works to fight off infections and how scientists are working to develop a universal flu vaccine that could protect us against every strain of the flu, even ones that don't exist yet. Learning about this exciting field of research not only expands our knowledge of how vaccines work, but also helps us understand the importance of public health initiatives.

Are you fascinated by the human heart and its complex workings? Do you want to be at the forefront of medical research and innovation? Then studying cardiology could be the perfect fit for you! Cardiology is the study of the heart and its functions, as well as the diagnosis and treatment of related diseases. It's a field that combines biology, physics, and medicine to understand the intricate mechanisms of the heart and how they affect our overall health. One of the most exciting aspects of cardiology is the potential for innovation and discovery. Researchers in this field are constantly developing new treatments and technologies to improve patient outcomes. For example, recent breakthroughs in stem cell research have opened up new possibilities for repairing damaged heart tissue. Some of the most well-known figures in cardiology include Dr. Robert Califf, former Commissioner of the FDA and a leading expert in cardiovascular disease, and Dr. Valentin Fuster, a world-renowned cardiologist who has made significant contributions to the study of atherosclerosis. As an undergraduate student of cardiology, you'll typically take courses in anatomy, physiology, pharmacology, and epidemiology, among others. You'll also have the opportunity to specialize in areas like electrophysiology, interventional cardiology, or cardiac imaging. After completing your degree, you'll be well-prepared for a range of careers in the healthcare industry. You could work as a cardiologist in a hospital or clinic, or pursue a career in medical research or medical device development. Some of the most popular employers in this field include the American Heart Association, Mayo Clinic, and the National Institutes of Health. To succeed in cardiology, you'll need to have a strong background in science and math, as well as excellent critical thinking and problem-solving skills. A passion for helping others and a desire to make a difference in people's lives are also key attributes for success in this field. So if you're ready to take on the challenge of studying the heart and its functions, consider a career in cardiology. Your work could help save lives and improve the health of people around the world!

Childhood cancer is a devastating disease that affects thousands of children every year. However, as cancer is more likely to occur in adults rather than children, research on childhood cancer is often underfunded, leading to fewer treatment options and lower survival rates. One of the biggest challenges in treating childhood cancer is the risk of long-term side effects from chemotherapy and radiation. These treatments can cause developmental delays, learning disabilities, and even secondary cancers later in life. As a result, new treatment strategies are being developed to minimize these risks. One of the most promising new approaches is immunotherapy, a type of treatment that harnesses the power of the immune system to attack cancer cells. CAR T-cell therapy, in which T-cells are genetically engineered to recognize and attack cancer cells, has shown particularly promising results in clinical trials. Another challenge in treating childhood cancer is the lack of targeted therapies. Unlike adult cancers, childhood cancers often have no known driver mutations that can be targeted with precision medicine. Researchers are working to identify new drug targets and develop new treatments that can attack cancer cells while sparing healthy cells. Dr. Kimberly Stegmaier, an oncologist and researcher at the Dana-Farber Cancer Institute, is one of the leading experts in childhood cancer research. She and her team are working to identify new drug targets and develop targeted therapies for childhood cancers. They are also studying the genetic and molecular characteristics of childhood cancers to better understand how they develop and how they can be treated. In conclusion, childhood cancer presents unique challenges that require innovative solutions. While underfunded research and the lack of targeted therapies have made progress difficult, recent developments in immunotherapy, such as CAR T-cell therapy, show promising results. As we continue to fight for a cure, let us also remember the children and families affected by this disease and strive to support them in any way we can.

China's updated regulations on gene editing in humans may not be enough to prevent regulatory negligence and ethical concerns, warns Dr Joy Zhang of Kent University. The regulations set requirements for ethical approval, supervision, and inspection, but experts worry they may not apply to the private sector. Gene editing is a controversial technique that could correct many inherited diseases, but raises the possibility of permanent changes to a person's genetic make-up. The world's leading scientists were stunned when a Chinese scientist claimed to have created the world's first gene-edited babies. This article explores the latest developments in the field of gene editing in China.

Can blood rejuvenation really extend human lifespan by 10 healthy years? Silicon Valley entrepreneurs invest millions into life extension projects. But is it ethical? Read on to explore the scientific and ethical debates surrounding lifespan extension technologies.