New research has identified gold-based compounds that could treat multidrug-resistant "superbugs", with some effectiveness against several bacteria. Antibiotic resistance is a global public health threat, and the development of new antibiotics has stalled. Gold metalloantibiotics, compounds with a gold ion at their core, could be a promising new approach. Dr. Sara M. Soto Gonzalez and colleagues studied the activity of 19 gold complexes against a range of multidrug-resistant bacteria isolated from patients. The gold compounds were effective against at least one bacterial species studied, with some displaying potent activity against several multidrug-resistant bacteria.

Discover the secret behind Gram-negative bacteria's armor-like outer membrane! A new study led by Professor Colin Kleanthous at the University of Oxford sheds light on how bacteria like E. coli construct their outer membrane to resemble body armor, with implications for developing antibiotics.

Stanford University researchers, in collaboration with other institutions, have developed a molecule that prevents the spike protein of the SARS-CoV-2 virus from twisting and infecting cells, including those with new variants. This new type of antiviral therapeutic, called the longHR2\_42 inhibitor, may be delivered via inhaler to treat early infections and prevent severe illness. The team's detailed understanding of the twisted structure of the virus's spike protein allowed them to create a longer molecule that is more effective than previous attempts to block the virus. Their groundbreaking research may lead to a promising solution to combat COVID-19.

Researchers have identified lipid differences in patients with alcohol-related liver disease that could lead to earlier detection and new treatments. Sphingomyelins were found to be significantly reduced in scarred liver tissue, potentially serving as a biomarker for ALD. Learn more about this breakthrough research and its implications for the diagnosis and treatment of ALD.

Chemotherapy is a type of cancer treatment that uses drugs to kill rapidly dividing cancer cells in the body. The drugs are delivered through pills and injections and are toxic to all cells in the body, including healthy ones. However, cancer cells are more susceptible to the effects of chemotherapy because they multiply rapidly. Chemotherapy drugs can damage hair follicles, cells of the mouth, gastrointestinal lining, reproductive system, and bone marrow, which can cause side effects such as hair loss, fatigue, infertility, nausea, and vomiting. Despite these side effects, chemotherapy has greatly improved the outlook for many cancer patients. Advances in treatment have led to up to 95% survival rates for testicular cancer and 60% remission rates for acute myeloid leukemia. Researchers are still developing more precise interventions to target cancer cells while minimizing harm to healthy tissues. Learning about chemotherapy can help high school students understand the science behind cancer treatment and the importance of ongoing research to improve outcomes for patients.

Have you ever wondered what happens to your blood after it's drawn at the doctor's office? Or how doctors diagnose illnesses and diseases? Enter the world of Medical Laboratory Science, where the magic happens behind the scenes. As a Medical Laboratory Scientist, your role is crucial in the healthcare industry. You'll use advanced laboratory techniques and equipment to analyze patient samples, such as blood, tissue, and bodily fluids, to help diagnose and treat diseases. You'll work with a team of healthcare professionals, including doctors and nurses, to provide accurate and timely results that inform patient care. But what makes this career so appealing? For starters, it's a constantly evolving field. With new technologies and discoveries, you'll always be learning and adapting to stay at the forefront of your profession. Plus, you'll have the satisfaction of knowing that your work directly impacts patient outcomes and helps save lives. In terms of duties, Medical Laboratory Scientists can specialize in a variety of areas, such as microbiology, hematology, or immunology. You may also work in related fields, such as research or public health. Typical tasks include analyzing samples, interpreting results, and communicating findings to healthcare providers. To become a Medical Laboratory Scientist, you'll need at least a Bachelor's degree in Medical Laboratory Science or a related field. Popular undergraduate programs include Biology, Chemistry, and Medical Technology. You'll also need to complete a clinical rotation and pass a certification exam. Helpful personal attributes for this career include attention to detail, critical thinking skills, and the ability to work well under pressure. You'll also need strong communication skills to effectively communicate with healthcare providers and patients. Job prospects for Medical Laboratory Scientists are strong, with a projected growth rate of 11% from 2018 to 2028. You can find job opportunities in a variety of settings, including hospitals, clinics, research labs, and government agencies. Notable employers include Mayo Clinic, Quest Diagnostics, and the Centers for Disease Control and Prevention. So if you're interested in a career that combines science, technology, and healthcare, consider exploring the world of Medical Laboratory Science. Who knows - you could be the next person to discover a life-saving breakthrough!

Do you have a passion for science and a desire to help people? If so, Optometry may be the perfect field of study for you. Optometry is a branch of medicine that focuses on the eyes and vision. It is a fascinating field that combines science, technology, and patient care to help people see clearly and live their best lives. Optometry is all about helping people to see the world around them. As an optometrist, you will use your knowledge of the eyes and vision to diagnose and treat a range of eye conditions, from simple refractive errors to more complex diseases such as glaucoma and cataracts. You will also help people to maintain their eye health and prevent vision problems from developing. One of the most exciting aspects of Optometry is the constant innovation and research that is taking place in the field. From new technologies that allow for more accurate diagnosis and treatment, to groundbreaking research into the causes and treatments of eye diseases, there is always something new and exciting happening in Optometry. At the undergraduate level, typical majors and modules include anatomy and physiology of the eye, optics, visual perception, and ocular disease. Students will also have the opportunity to gain practical experience through clinical placements and internships. After completing their undergraduate degree, students can go on to specialize in areas such as pediatric optometry, contact lenses, or vision therapy. With a degree in Optometry, there are a range of potential job opportunities available. Optometrists can work in private practice, hospitals, clinics, or for government agencies. Some notable employers in the field include Bausch + Lomb, Johnson & Johnson, and Essilor. To succeed in Optometry, students should have a strong background in science, particularly biology and chemistry. They should also possess excellent communication and interpersonal skills, as they will be working closely with patients on a daily basis. If you are passionate about science and helping people, a degree in Optometry may be the perfect choice for you.

Have you ever wondered what it takes to be a heart doctor? Well, look no further because we've got the inside scoop on the exciting and rewarding field of cardiology! As a cardiologist, you'll be responsible for diagnosing and treating heart conditions, helping patients live longer, healthier lives. From heart attacks to arrhythmias, you'll have the knowledge and skills to provide life-saving care to those in need. But being a cardiologist isn't just about saving lives, it's also about preventing heart disease. You'll work with patients to develop healthy habits and manage risk factors, like high blood pressure and high cholesterol. And the best part? The field of cardiology is constantly evolving, with new treatments and technologies being developed all the time. You'll have the opportunity to stay at the forefront of medical advancements and make a real difference in the lives of your patients. Typical duties of a cardiologist include performing diagnostic tests, like electrocardiograms and echocardiograms, prescribing medication and lifestyle changes, and performing procedures like angioplasty and stenting. There are also many areas of specialisation within the field, such as electrophysiology and interventional cardiology. To become a cardiologist, you'll need to complete extensive education and training. This typically includes a bachelor's degree in a relevant field, such as biology or chemistry, followed by medical school and a residency in internal medicine. After that, you'll complete a fellowship in cardiology, where you'll gain specialised knowledge and skills. Helpful personal attributes for a career in cardiology include strong communication skills, attention to detail, and a passion for helping others. You'll also need to be able to work well under pressure and make quick decisions in life-or-death situations. Job prospects for cardiologists are excellent, with a growing demand for heart specialists around the world. Some notable potential employers include the Mayo Clinic, Cleveland Clinic, and Johns Hopkins Hospital, among many others. So, if you're looking for a challenging and rewarding career that allows you to make a real difference in the lives of others, consider becoming a cardiologist. Your heart (and your patients' hearts) will thank you!

Tardigrades, also known as water bears, can survive extreme environments by entering a state of suspended animation and revitalizing decades later, and a UCLA chemist used this mechanism to develop a polymer called pTrMA that stabilizes drugs at high temperatures and over extended periods. This innovation could improve drug access, reduce waste, and save lives.

Have you ever considered a career in Oncology? As an oncologist, you would be at the forefront of cancer care, helping patients navigate through one of the most challenging times of their lives. Not only would you be making a significant impact on the lives of those affected by cancer, but you would also be part of a field that is constantly evolving and advancing. As an oncologist, you would work with a team of healthcare professionals to diagnose and treat cancer patients. You would be responsible for developing treatment plans, monitoring patients' progress, and providing emotional support to patients and their families. Oncologists also play a vital role in cancer research, helping to develop new treatments and therapies. There are several specializations within the field of oncology, including medical oncology, radiation oncology, and surgical oncology. Medical oncologists focus on using chemotherapy and other medications to treat cancer, while radiation oncologists use radiation therapy to destroy cancer cells. Surgical oncologists, on the other hand, perform surgeries to remove cancerous tumors. To become an oncologist, you will need to complete a medical degree, followed by a residency in oncology. Popular undergraduate programs for aspiring oncologists include biology, chemistry, and pre-med. In addition to formal education, oncologists must possess excellent communication and interpersonal skills, as well as a strong desire to help others. Job prospects for oncologists are excellent, with a growing demand for cancer care worldwide. There are many potential employers in both the public and private sectors, including hospitals, research institutions, and pharmaceutical companies. Notable employers include Memorial Sloan Kettering Cancer Center, MD Anderson Cancer Center, and the National Cancer Institute. In conclusion, a career in oncology is both challenging and rewarding. By pursuing this career, you would be making a significant impact on the lives of cancer patients and their families, while also contributing to the advancement of cancer research and treatment. So if you have a passion for helping others and a desire to make a difference in the world, consider a career in oncology.

Are you fascinated by the science behind the drugs that keep us healthy and cure our ailments? Do you have a passion for research and innovation? Then studying Pharmaceutical Research might be the perfect field for you. Pharmaceutical Research is a dynamic and ever-evolving field that combines chemistry, biology, and pharmacology to develop new drugs and therapies. It is a field that has a direct impact on people's lives, as it is responsible for the development of life-saving medications that improve our quality of life. One of the most exciting aspects of Pharmaceutical Research is the potential for groundbreaking discoveries. From the development of vaccines to the discovery of new treatments for diseases, the possibilities are endless. For example, the Pfizer-BioNTech COVID-19 vaccine was developed through extensive research and clinical trials, showcasing the real-world impact of Pharmaceutical Research. At the undergraduate level, students can expect to study a range of subjects, including biochemistry, pharmacology, and drug discovery. They will also have the opportunity to work on research projects and gain hands-on experience in the field. Some potential areas of further specialization include drug formulation, clinical research, and regulatory affairs. Graduates can go on to work in a variety of industries, including pharmaceuticals, biotech, and healthcare. Some notable employers in the field include Pfizer, Merck, and Novartis. These companies offer exciting career opportunities for graduates, including roles in research and development, quality assurance, and regulatory affairs. To succeed in Pharmaceutical Research, students should have a strong foundation in chemistry and biology. They should also possess excellent analytical and problem-solving skills, as well as a passion for innovation and discovery. If you are interested in a career in Pharmaceutical Research, there are many exciting opportunities waiting for you. Start exploring this fascinating field today and see where it takes you!

An interdisciplinary UCLA research team has developed a tiny implantable device called SymphNode, which has been shown to be able to drive tumours into remission, eliminate metastasis, and prevent the growth of new tumours, resulting in longer survival in mice. This groundbreaking technology may decrease the risk of cancer returning, making it a potential addition to chemotherapy or other first-step treatments for a variety of cancers.

Have you ever wondered why a black eye turns blue, then green, then yellow, and finally brown before disappearing? It's all because of your hemoglobin, the compound in red blood cells that brings oxygen to your body. When you get hit, the blow crushes tiny blood vessels called capillaries, and red blood cells ooze out of the broken capillaries into the surrounding tissue. From the outside of your skin, this mass of cells looks bluish-black, which is where we get the term, "black and blue". Learning about hemoglobin and how it works in your body can be fascinating and practical knowledge that can help you understand how your body works. It's an example of how exploring academic topics through reading, reflection, and writing can inspire you to learn more about the world around you.

Do you have a passion for helping others and a fascination with the human eye? If so, a career in optometry could be the perfect fit for you! Optometrists are healthcare professionals who specialize in diagnosing and treating vision problems and eye diseases. They play a vital role in helping people maintain healthy eyes and clear vision. As an optometrist, you'll have the opportunity to work with patients of all ages, from children to seniors. You'll use state-of-the-art technology to examine patients' eyes and diagnose problems such as nearsightedness, farsightedness, and astigmatism. You'll also be able to detect and treat eye diseases such as glaucoma, cataracts, and macular degeneration. One of the most appealing aspects of a career in optometry is the ability to make a real difference in people's lives. Imagine helping a child see clearly for the first time or saving someone's vision by detecting a serious eye disease early on. Optometrists have the power to improve their patients' quality of life in meaningful ways. In addition to traditional optometry, there are many areas of specialization within the field. Some optometrists choose to focus on pediatric optometry, working with children to ensure they have healthy eyes and clear vision. Others specialize in contact lenses, helping patients find the perfect lenses to fit their unique needs. And still others focus on low vision, working with patients who have severe visual impairments to help them navigate the world around them. To become an optometrist, you'll need to complete a Doctor of Optometry (OD) degree from an accredited optometry school. Popular undergraduate majors for aspiring optometrists include biology, chemistry, and physics. In addition to completing a rigorous academic program, you'll also need to pass a national board exam to become licensed to practice. Helpful personal attributes for a career in optometry include strong communication skills, attention to detail, and a passion for helping others. You'll also need to be comfortable using technology and working with a wide range of patients. Job prospects for optometrists are strong, with a projected growth rate of 10% over the next decade. Optometrists can work in a variety of settings, from private practices to hospitals to retail stores. Some notable employers in the field include LensCrafters, Kaiser Permanente, and the U.S. Department of Veterans Affairs. So if you're looking for a career that combines cutting-edge technology, meaningful patient interactions, and the opportunity to make a real difference in people's lives, consider a career in optometry!

Did you know that a medicine we use today, aspirin, was discovered over 4,000 years ago by the ancient Sumerians? They found that by eating the bark of a particular tree, their pain disappeared. This discovery influenced the future of medicine and led to the development of aspirin. Aspirin's active ingredient is found in willow trees and other wild plants and was used by ancient cultures to ease pain, fever, and inflammation. The compound that made this possible, salicin, was identified and purified in the mid-18th century. Aspirin became synonymous with acetylsalicylic acid and was found to ease not just pain but also many inflammation-related problems. Research has also uncovered aspirin's risks, but it has been found to reduce heart attack risk and potentially reduce the risk of getting and dying from cancer. Learning about aspirin's history and benefits can inspire you to explore the world of medicine and the potential for discovering new treatments.

Want to know the secret to successful and sustainable weight loss? According to a recent study by Stanford Medicine researchers, it's all about the bacteria in your gut and the biomarkers in your body! The study found that certain gut microbiome ecologies and amounts of proteins can predict whether you will be successful at losing weight and keeping it off. So, are you ready to unlock the power of your gut and biomarkers for weight loss success?

Are you curious about the tiny viruses that inhabit your body? MIT Technology Review's biotech newsletter, The Checkup, explores the world of bacteriophages, or "phages" for short. These microscopic viruses have the potential to treat bacterial infections, but they've been largely abandoned in favor of antibiotics. With antimicrobial resistance on the rise, interest in phage therapy is making a comeback. Learn about the diversity and specificity of phages, and how they could be engineered to target specific bacteria. Discover the potential of phage therapy and the challenges that need to be overcome in this fascinating article.

Are you fascinated by the human body and how it works? Do you dream of becoming a doctor and making a difference in people's lives? Then pre-medicine might be the perfect field of study for you! Pre-medicine is a challenging and rewarding field that prepares students for medical school and a career in healthcare. It encompasses a wide range of subjects, from biology and chemistry to anatomy and physiology. Through this field of study, you will gain a deep understanding of the human body and the diseases that affect it. Research in pre-medicine is constantly evolving, with new innovations and breakthroughs being made all the time. For example, recent studies have shown that stem cell therapy may be a promising treatment for a variety of conditions, from heart disease to Parkinson's. Additionally, academic figures like Dr. Anthony Fauci have made significant contributions to the field, particularly in the area of infectious diseases. At the undergraduate level, typical majors and modules include biology, chemistry, and biochemistry. These foundational courses provide a strong basis for further specialization in areas such as neuroscience, pharmacology, or genetics. For example, you could become a specialist in neurology and work with patients who have disorders like Alzheimer's or Parkinson's. The potential career paths for pre-med graduates are vast and varied. Many go on to become doctors, working in fields such as pediatrics, cardiology, or oncology. Others pursue careers in related fields, such as medical research or public health. Notable employers include world-renowned hospitals such as the Mayo Clinic and Johns Hopkins, as well as organizations like the World Health Organization and Doctors Without Borders. To succeed in pre-medicine, it's important to have a strong work ethic, a passion for learning, and excellent communication skills. You should also have a keen interest in science and a desire to make a difference in people's lives. In conclusion, pre-medicine is an exciting and challenging field of study that offers a wealth of opportunities for those who are passionate about healthcare. With a strong foundation in biology and chemistry, you can specialize in a variety of areas and pursue a rewarding career in medicine or related fields. So if you're ready to make a difference in the world, consider studying pre-medicine and joining the ranks of healthcare professionals who are changing lives every day.

Discover how human evolution has led to unique diseases like knee osteoarthritis, affecting millions worldwide. Professor Terence D. Capellini shares genetic research on the link between bipedalism and knee osteoarthritis, and how identifying high-risk patients at an early age can inform future therapies. Explore the Developmental and Evolutionary Genetics Lab's work and hypotheses published in his 2020 paper "Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk." Join the Harvard Museums of Science & Culture's ongoing series to learn more.

Sugar is a staple in the modern diet, but it can also be a health hazard when consumed in excess. As a result, sugar substitutes have become increasingly popular in recent years. In this write-up, we will explore the science and effectiveness of sugar substitutes, including the various types of sugar substitutes and their effects on the human body. One of the most widely used sugar substitutes is aspartame, which is commonly found in diet soda and other low-calorie products. While aspartame has been the subject of much debate, studies have shown that it is safe for human consumption in moderate amounts. Another popular sugar substitute is stevia, which is derived from a plant and has no calories. Stevia has been shown to be an effective sugar substitute for people with diabetes, as it does not raise blood sugar levels. But not all sugar substitutes are created equal. For example, sugar alcohols like xylitol and erythritol can cause digestive issues when consumed in large quantities. And some artificial sweeteners like saccharin have been linked to an increased risk of cancer. Leading academics in the field of sugar substitutes include Dr. Marion Nestle, a professor of nutrition at New York University, and Dr. Richard Mattes, a professor of nutrition science at Purdue University. These experts have conducted extensive research on the effects of sugar substitutes on the human body and can provide valuable insights into the topic. The science and effectiveness of sugar substitutes are fascinating topics that can inspire students to explore the world of nutrition and health. By encouraging independent exploration and self-directed projects, we can empower high school students to take ownership of their learning and develop a lifelong love of academic inquiry.