Have you ever wondered why some people are more adventurous than others? Geneticists are trying to figure out if certain genes can explain differences in behavior, like thrill-seeking, aggression, and nurturing. Research has shown that the genetics behind complex behavior is trickier than we first thought, and differences in behavior are not the result of one or a handful of genes. For example, the activity of 4,000 out of 15,000 genes in fruit flies determines how tough they will get with each other. If the genetics of behavior is that complicated in a fruit fly, imagine how complicated it would be for a human. Learning about the genetics of behavior can help us understand ourselves and others better, and it can also lead to practical applications in fields like medicine and psychology.

A groundbreaking study from Weill Cornell Medicine has identified four distinct subtypes of autism based on brain activity and behavior. Machine learning was used to analyze neuroimaging data from 299 people with autism and 907 neurotypical individuals, revealing patterns of brain connections linked to behavioral traits. The study shows promise for personalized therapies and new approaches to diagnosis and treatment.

Are you curious about what happens when you sleepwalk? Sleepwalking is a fascinating behavior that many people experience at least once in their lives. When you sleepwalk, your brain's control hub is turned off, and your body is guided by specialized nerve cells. While most sleepwalkers only do basic things, in rare cases, some may perform more complex tasks. Sleep terrors, another sleep disorder, are more common in young children and involve sudden jolts out of bed or running away. Researchers are still unclear about what causes sleepwalking, but it's thought to run in families or be triggered by stress, sleep disorders, or sleep deprivation. Learning more about sleepwalking can not only help you understand how your brain works, but also help you establish healthy sleep habits and promote overall wellness to reduce chances of you sleepwalking.

DNA is a molecule that holds the secrets of life within its code, and it's waiting for you to explore it! This amazing molecule determines our traits, from our physical appearance to our personalities, and it can also tell us about our ancestry, our risk of diseases, and much more. Leading academics in the field of genetics, such as James Watson and Francis Crick, made major contributions to our understanding of DNA by discovering its structure and how it stores and transfers genetic information. Watson and Crick's discovery of the double helix structure of DNA was a major turning point in the field of genetics and opened up new avenues for scientific research. In the early 1990s, the Human Genome Project was launched to map all of the genes in human DNA. This project was a huge success and has had a profound impact on the field of genetics. It allowed scientists to identify specific genes that are associated with different diseases, such as cancer, and has paved the way for new treatments and cures. One of the most fascinating things about DNA is that every person's DNA is 99.9% identical to every other person's DNA. It's the remaining 0.1% that makes each of us unique! Our DNA also contains fascinating stories about our ancestors and their migrations. For example, DNA testing can tell us where our ancestors came from and how they migrated across the world. This is known as genetic genealogy, and it's an exciting field that combines genetics and history. Another fascinating aspect of DNA is its role in evolution. Charles Darwin's theory of evolution by natural selection states that species change over time through the process of natural selection. This process occurs because certain traits that provide an advantage in survival and reproduction become more common in a population over time. DNA mutations can lead to changes in traits, and over many generations, these changes can accumulate and result in new species. By exploring the world of DNA, you will not only deepen your understanding of genetics and biology, but also gain a new appreciation for the complexities and wonders of life. So go ahead, unlock the secrets of life with the power of DNA!

Unlock the secrets of Alzheimer's disease with single-cell profiling! MIT scientists have made rapid progress in understanding Alzheimer's disease by using single-cell profiling technologies. By analyzing genetic activity in individual cells, they have identified five main areas of cellular function, or "pathways," that are disrupted in the disease. These findings hold strong potential for explaining the disease and developing meaningful therapies.

Revolutionize cancer treatment with a new approach - turning cancer cells into cancer-killing vaccines! Researchers at Brigham and Women's Hospital and Harvard-affiliate are developing a cell therapy that eliminates tumours and trains the immune system to prevent future cancer outbreaks.

A study of rockfish longevity has revealed a set of genes controlling their aging process, leading to the discovery of a previously unappreciated group of genes associated with extended lifespan in humans. The findings show that the same pathways that promote longevity in rockfish also promote longevity in humans. The study identified two major metabolic systems that regulate lifespan in rockfish: the insulin-signaling pathway, which prior research has shown plays a major role in regulating the lifespan of many different animals, and the previously unappreciated flavonoid metabolism pathway. These results provide insights into how to prevent or delay common human diseases of old age.

Did you know that selecting the embryo with the lowest risk for a given disease can cut the risk for that disease by almost half? This is particularly true for disorders such as schizophrenia and Crohn’s disease. However, the selection process may not lead to significant improvements in non-disease traits such as intelligence. Moreover, the use of preimplantation genetic screening (PES) raises concerns about psychological well-being, social values, and ethics. Learn more about the potential benefits and risks of PES, and how it may impact our society and individuality.

Stress is an inevitable part of life that can cause physical and mental health issues. However, taking on reasonable challenges can help condition the brain to handle stressful situations, making individuals more resilient. When faced with stress, the body's response is to fight or flee, releasing hormones that improve focus, reflexes, and senses. The brain's fear sensor, the amygdala, alerts the hypothalamus that something is wrong, which then activates the adrenal glands to release epinephrine and cortisol. While modern stressors are usually not life-threatening, taking on reasonable challenges, such as public speaking or standing up to a friend, can help the brain gain power and shut down the amygdala, making individuals more resilient to stress. By learning how to handle stress, students can benefit both intellectually and practically, improving their mental and physical health and their ability to handle challenging situations.

Can blood rejuvenation really extend human lifespan by 10 healthy years? Silicon Valley entrepreneurs invest millions into life extension projects. But is it ethical? Read on to explore the scientific and ethical debates surrounding lifespan extension technologies.

Are you interested in how the brain works? A new study from Cornell University reveals that neurons in the hippocampus, a key area of the brain, have different functions based on their genetic identity. This could lead to a better understanding of the brain's computational flexibility and memory capacity, and inform potential treatments for diseases like Alzheimer's. Check out the full article in the journal Neuron to learn more!

China's updated regulations on gene editing in humans may not be enough to prevent regulatory negligence and ethical concerns, warns Dr Joy Zhang of Kent University. The regulations set requirements for ethical approval, supervision, and inspection, but experts worry they may not apply to the private sector. Gene editing is a controversial technique that could correct many inherited diseases, but raises the possibility of permanent changes to a person's genetic make-up. The world's leading scientists were stunned when a Chinese scientist claimed to have created the world's first gene-edited babies. This article explores the latest developments in the field of gene editing in China.

Severe stress triggers biological age to increase, but it can be reversed. Surgery, pregnancy, and COVID-19 are studied in humans and mice. Researchers found that biological age increased in situations of severe physiological stress but was restored when the stressful situation resolved. This study challenges the concept that biological age can only increase over a person’s lifetime and suggests that it may be possible to identify interventions that could slow or even partially reverse biological age.

In just a few thousand years, northern Europeans evolved to digest milk, a feat that was once impossible for adult humans. Scientists now believe that exceptional stressors like famines and pathogens may have driven this genetic change, making the ability to digest milk extra valuable. This study, published in Nature and led by experts from the University of Bristol and University College London, sheds light on the evolution of lactose tolerance and rewrites the textbooks on why drinking milk was an advantage.

Are you curious about the tiny viruses that inhabit your body? MIT Technology Review's biotech newsletter, The Checkup, explores the world of bacteriophages, or "phages" for short. These microscopic viruses have the potential to treat bacterial infections, but they've been largely abandoned in favor of antibiotics. With antimicrobial resistance on the rise, interest in phage therapy is making a comeback. Learn about the diversity and specificity of phages, and how they could be engineered to target specific bacteria. Discover the potential of phage therapy and the challenges that need to be overcome in this fascinating article.

Singapore's national flower, Papilionanthe Miss Joaquim, has had its entire genetic blueprint decoded, revealing natural products with antioxidant properties and distinctive colors. The study, published in Communications Biology, could lead to future research in gene and metabolite engineering, as well as the discovery of bioactive compounds for healthcare purposes. The collaboration between A\*STAR's Genome Institute of Singapore and SingHealth Duke-NUS Institute of Biodiversity Medicine showcases the power of genetic sequencing technology in preserving and studying Singapore's plant biodiversity.

Disgust is a universal emotion that serves a vital purpose in human survival. This complex emotion can protect us from harmful substances and dangerous situations. But where did this emotion come from, and how did it evolve? One theory suggests that disgust evolved as a protective mechanism against infectious diseases. For example, our ancestors who avoided eating rotten or contaminated food were less likely to contract deadly illnesses. As a result, the disgust response became ingrained in our brains and bodies as a way to protect ourselves. But what happens when disgust becomes a phobia? A phobia is an irrational and persistent fear of a specific object, situation, or activity. For example, arachnophobia is a fear of spiders, and mysophobia is a fear of germs. While these fears may seem irrational, they can also be traced back to our evolutionary past. One leading academic in the field of disgust is Valerie Curtis, a Professor of Hygiene at the London School of Hygiene & Tropical Medicine. Curtis has dedicated her career to understanding the psychological and cultural aspects of hygiene and cleanliness. In her book, "Don't Look, Don't Touch: The Science Behind Revulsion," Curtis argues that disgust is not just a physical response, but also a cultural and social construct. Another academic, Paul Rozin, a Professor of Psychology at the University of Pennsylvania, has studied the cross-cultural nature of disgust. Rozin found that certain types of disgust, such as the disgust for animal products, are not universal but are instead shaped by cultural and religious beliefs. In conclusion, disgust may be an uncomfortable emotion, but it is also a crucial one for our survival. By understanding the evolutionary roots of disgust and its role in our lives, we can better appreciate this complex emotion and use it to our advantage.

Are you curious about why you and your siblings, even fraternal twins, are so different? The answer lies in genetics, a fascinating topic that explains why we have predispositions for certain physical traits, mental abilities, behaviors, and attitudes. Twin studies provide invaluable insights into how genes and environments interact to shape who we are. As Dr. Nancy Segal, a psychology professor, explains, genetics is not everything, but it explains a great deal of why we differ. By understanding the probabilistic nature of genes, we can appreciate the complexity of human behavior and diversity. By engaging in activities such as reading, reflecting, writing, and pursuing self-directed projects related to genetics, you can uncover the mysteries of your own genetic predispositions. This process can also help you discover new interests and passions that may shape your future academic and career paths.

Scientists sequence Beethoven's genome from locks of hair, revealing new insights into his health and ancestry. The study, led by Cambridge University and other institutions, uncovers genetic risk factors for liver disease and an infection with Hepatitis B virus. Beethoven's hearing loss remains a mystery, but his genomic data rules out coeliac disease and lactose intolerance as potential causes. The study sheds light on the composer's health problems, including chronic gastrointestinal complaints and a severe liver disease that likely contributed to his death at age 56.

Did you know that adults catch more than 150 colds throughout their lives, and that a single family of viruses causes 30 to 50% of all colds? Understanding the complex relationship between viruses and our immune systems is not only fascinating, but also highly relevant to our daily lives. By reading about pleconaril, rhinovirus, and CRISPR, you'll learn about the science behind vaccines and antiviral drugs, and how they could help us tackle the common cold. But beyond that, exploring this topic will help you appreciate the incredible complexity and resilience of our immune systems, and the importance of maintaining our health. So grab a cup of tea and your favorite notebook, and get ready to dive into the fascinating world of viruses and immune systems!