Did you know that a medicine we use today, aspirin, was discovered over 4,000 years ago by the ancient Sumerians? They found that by eating the bark of a particular tree, their pain disappeared. This discovery influenced the future of medicine and led to the development of aspirin. Aspirin's active ingredient is found in willow trees and other wild plants and was used by ancient cultures to ease pain, fever, and inflammation. The compound that made this possible, salicin, was identified and purified in the mid-18th century. Aspirin became synonymous with acetylsalicylic acid and was found to ease not just pain but also many inflammation-related problems. Research has also uncovered aspirin's risks, but it has been found to reduce heart attack risk and potentially reduce the risk of getting and dying from cancer. Learning about aspirin's history and benefits can inspire you to explore the world of medicine and the potential for discovering new treatments.

In just a few thousand years, northern Europeans evolved to digest milk, a feat that was once impossible for adult humans. Scientists now believe that exceptional stressors like famines and pathogens may have driven this genetic change, making the ability to digest milk extra valuable. This study, published in Nature and led by experts from the University of Bristol and University College London, sheds light on the evolution of lactose tolerance and rewrites the textbooks on why drinking milk was an advantage.

Silphion, a golden-flowered plant once prized by the Greeks and Romans for its medicinal and culinary uses, disappeared from the ancient world. But a professor in Turkey may have rediscovered the last holdouts of the plant, which was once valued as highly as gold. Ferula drudeana, a plant with similar characteristics, may be the modern-day version of silphion, with potential for medical breakthroughs. Explore the fascinating story of a plant that was the first recorded extinction and the search for its rediscovery.

Chocolate, a food loved by many, has a rich history dating back 2,500 years. The Mayans and Aztecs consumed chocolate as a drink and used its beans as currency and in ceremonies. When the Spanish invaded and colonized the areas where it was found, they adopted it for their own use, and it slowly spread to other European countries. Chocolate was considered a rich person's beverage, imbued with health and spiritual properties, and was even claimed to be an aphrodisiac. Today, chocolate has become polarized, from cheap, sugary stuff to high-end black bars of joy. Early studies suggest that small doses of very dark chocolate, rich in anti-oxidants, theobromine, and caffeine, may have health benefits. Learning about the history and science behind chocolate can be both intellectually stimulating and practically beneficial to our health.

Scientists sequence Beethoven's genome from locks of hair, revealing new insights into his health and ancestry. The study, led by Cambridge University and other institutions, uncovers genetic risk factors for liver disease and an infection with Hepatitis B virus. Beethoven's hearing loss remains a mystery, but his genomic data rules out coeliac disease and lactose intolerance as potential causes. The study sheds light on the composer's health problems, including chronic gastrointestinal complaints and a severe liver disease that likely contributed to his death at age 56.

Tardigrades, also known as water bears, can survive extreme environments by entering a state of suspended animation and revitalizing decades later, and a UCLA chemist used this mechanism to develop a polymer called pTrMA that stabilizes drugs at high temperatures and over extended periods. This innovation could improve drug access, reduce waste, and save lives.

The discovery of the structure of DNA is one of the most important scientific achievements in human history. While Watson and Crick are often credited with this breakthrough, Rosalind Franklin's scientific contributions have been vastly underplayed. Franklin faced sexism and isolation from her colleagues, but she kept working and obtained Photo 51, the most famous x-ray image of DNA. Her calculations led her to the same conclusion as Watson and Crick, but her manuscript was published last, making it look like her experiments just confirmed their breakthrough instead of inspiring it. Franklin's work revolutionized medicine, biology, and agriculture. Learning about her story will not only provide insight into the history of science but also inspire students to pursue their passions regardless of societal barriers.

The world of science is constantly evolving, and with it comes new discoveries that can benefit humanity. However, there are also risks associated with scientific research, particularly in the field of biotechnology. Gain of function work involves manipulating the DNA of microorganisms to give them new abilities, which can be used in vaccine production and cancer treatments. However, this work also includes engineering superbugs that could cause a global pandemic if they escape from the lab. While virologists argue that this research could help us prepare for future pandemics, critics believe that the risks outweigh the benefits. To minimize the risk of lab leaks, experts suggest creating international databases of leaks, near-misses, and fixes, as well as developing a robust pandemic early warning system. As students, it is important to understand the benefits and risks of scientific research and to be aware of the measures being taken to minimize the risks associated with it.

Disgust is a universal emotion that serves a vital purpose in human survival. This complex emotion can protect us from harmful substances and dangerous situations. But where did this emotion come from, and how did it evolve? One theory suggests that disgust evolved as a protective mechanism against infectious diseases. For example, our ancestors who avoided eating rotten or contaminated food were less likely to contract deadly illnesses. As a result, the disgust response became ingrained in our brains and bodies as a way to protect ourselves. But what happens when disgust becomes a phobia? A phobia is an irrational and persistent fear of a specific object, situation, or activity. For example, arachnophobia is a fear of spiders, and mysophobia is a fear of germs. While these fears may seem irrational, they can also be traced back to our evolutionary past. One leading academic in the field of disgust is Valerie Curtis, a Professor of Hygiene at the London School of Hygiene & Tropical Medicine. Curtis has dedicated her career to understanding the psychological and cultural aspects of hygiene and cleanliness. In her book, "Don't Look, Don't Touch: The Science Behind Revulsion," Curtis argues that disgust is not just a physical response, but also a cultural and social construct. Another academic, Paul Rozin, a Professor of Psychology at the University of Pennsylvania, has studied the cross-cultural nature of disgust. Rozin found that certain types of disgust, such as the disgust for animal products, are not universal but are instead shaped by cultural and religious beliefs. In conclusion, disgust may be an uncomfortable emotion, but it is also a crucial one for our survival. By understanding the evolutionary roots of disgust and its role in our lives, we can better appreciate this complex emotion and use it to our advantage.

Chemotherapy is a type of cancer treatment that uses drugs to kill rapidly dividing cancer cells in the body. The drugs are delivered through pills and injections and are toxic to all cells in the body, including healthy ones. However, cancer cells are more susceptible to the effects of chemotherapy because they multiply rapidly. Chemotherapy drugs can damage hair follicles, cells of the mouth, gastrointestinal lining, reproductive system, and bone marrow, which can cause side effects such as hair loss, fatigue, infertility, nausea, and vomiting. Despite these side effects, chemotherapy has greatly improved the outlook for many cancer patients. Advances in treatment have led to up to 95% survival rates for testicular cancer and 60% remission rates for acute myeloid leukemia. Researchers are still developing more precise interventions to target cancer cells while minimizing harm to healthy tissues. Learning about chemotherapy can help high school students understand the science behind cancer treatment and the importance of ongoing research to improve outcomes for patients.

DNA is a molecule that holds the secrets of life within its code, and it's waiting for you to explore it! This amazing molecule determines our traits, from our physical appearance to our personalities, and it can also tell us about our ancestry, our risk of diseases, and much more. Leading academics in the field of genetics, such as James Watson and Francis Crick, made major contributions to our understanding of DNA by discovering its structure and how it stores and transfers genetic information. Watson and Crick's discovery of the double helix structure of DNA was a major turning point in the field of genetics and opened up new avenues for scientific research. In the early 1990s, the Human Genome Project was launched to map all of the genes in human DNA. This project was a huge success and has had a profound impact on the field of genetics. It allowed scientists to identify specific genes that are associated with different diseases, such as cancer, and has paved the way for new treatments and cures. One of the most fascinating things about DNA is that every person's DNA is 99.9% identical to every other person's DNA. It's the remaining 0.1% that makes each of us unique! Our DNA also contains fascinating stories about our ancestors and their migrations. For example, DNA testing can tell us where our ancestors came from and how they migrated across the world. This is known as genetic genealogy, and it's an exciting field that combines genetics and history. Another fascinating aspect of DNA is its role in evolution. Charles Darwin's theory of evolution by natural selection states that species change over time through the process of natural selection. This process occurs because certain traits that provide an advantage in survival and reproduction become more common in a population over time. DNA mutations can lead to changes in traits, and over many generations, these changes can accumulate and result in new species. By exploring the world of DNA, you will not only deepen your understanding of genetics and biology, but also gain a new appreciation for the complexities and wonders of life. So go ahead, unlock the secrets of life with the power of DNA!

Have you ever wondered why a black eye turns blue, then green, then yellow, and finally brown before disappearing? It's all because of your hemoglobin, the compound in red blood cells that brings oxygen to your body. When you get hit, the blow crushes tiny blood vessels called capillaries, and red blood cells ooze out of the broken capillaries into the surrounding tissue. From the outside of your skin, this mass of cells looks bluish-black, which is where we get the term, "black and blue". Learning about hemoglobin and how it works in your body can be fascinating and practical knowledge that can help you understand how your body works. It's an example of how exploring academic topics through reading, reflection, and writing can inspire you to learn more about the world around you.

The Forgetting by David Shenk is a poignant and meticulously researched account of Alzheimer's disease, which affects almost half of those over 85 and kills nearly 100,000 Americans annually. Shenk delves into the social, medical, and spiritual implications of the disease, as well as its impact on the lives of its victims and their families. He also traces the history of Alzheimer's, suggesting that it may have afflicted such luminaries as Jonathan Swift and Ralph Waldo Emerson. This searing and engaging book offers a sympathetic and ultimately hopeful portrait of a disease that will touch the lives of virtually everyone. Recommended for anyone interested in the medical, social, and spiritual implications of Alzheimer's disease, The Forgetting is a must-read. Shenk's scrupulous research and moving account of the disease's impact on its victims and their families will be of particular interest to students studying gerontology, social work, psychology, and medicine. The book's exploration of the history of Alzheimer's and its possible links to famous figures such as Jonathan Swift and Ralph Waldo Emerson will also appeal to those interested in literary and cultural studies. Ultimately, The Forgetting is a powerful and encouraging portrait of a disease that affects millions of people worldwide.

Are you interested in science and making a difference in people's lives? A career in pharmaceutical research might be just what you're looking for! Pharmaceutical research is an exciting field that involves discovering and developing new drugs and therapies to treat and cure diseases. As a pharmaceutical researcher, you will have the opportunity to work on cutting-edge research projects that could change the lives of millions of people. For example, did you know that the development of the COVID-19 vaccines is a result of years of pharmaceutical research? You could be part of the next breakthrough in medicine! In this field, your typical duties will include conducting laboratory experiments, analyzing data, developing new drugs, and testing their safety and effectiveness. You may also specialize in a particular area, such as drug design, pharmacology, or clinical research. To become a pharmaceutical researcher, you will need to pursue a degree in a relevant field, such as chemistry, biology, or pharmacology. Popular undergraduate programs and majors include Biochemistry, Pharmaceutical Sciences, and Medicinal Chemistry. A graduate degree in pharmaceutical research is also highly desirable and may be required for some positions. Helpful personal attributes for this field include strong critical thinking skills, attention to detail, and excellent communication skills. A passion for science and a desire to make a difference in the world are also important. The job prospects for pharmaceutical researchers are promising. With the aging population and increasing demand for new drugs and therapies, the demand for skilled researchers is expected to grow. Notable and attractive potential employers in this field include pharmaceutical companies such as Pfizer, Merck, and Novartis, as well as government agencies such as the National Institutes of Health (NIH) and the Food and Drug Administration (FDA).

Have you ever wondered what happens to your blood after it's drawn at the doctor's office? Or how doctors diagnose illnesses and diseases? Enter the world of Medical Laboratory Science, where the magic happens behind the scenes. As a Medical Laboratory Scientist, your role is crucial in the healthcare industry. You'll use advanced laboratory techniques and equipment to analyze patient samples, such as blood, tissue, and bodily fluids, to help diagnose and treat diseases. You'll work with a team of healthcare professionals, including doctors and nurses, to provide accurate and timely results that inform patient care. But what makes this career so appealing? For starters, it's a constantly evolving field. With new technologies and discoveries, you'll always be learning and adapting to stay at the forefront of your profession. Plus, you'll have the satisfaction of knowing that your work directly impacts patient outcomes and helps save lives. In terms of duties, Medical Laboratory Scientists can specialize in a variety of areas, such as microbiology, hematology, or immunology. You may also work in related fields, such as research or public health. Typical tasks include analyzing samples, interpreting results, and communicating findings to healthcare providers. To become a Medical Laboratory Scientist, you'll need at least a Bachelor's degree in Medical Laboratory Science or a related field. Popular undergraduate programs include Biology, Chemistry, and Medical Technology. You'll also need to complete a clinical rotation and pass a certification exam. Helpful personal attributes for this career include attention to detail, critical thinking skills, and the ability to work well under pressure. You'll also need strong communication skills to effectively communicate with healthcare providers and patients. Job prospects for Medical Laboratory Scientists are strong, with a projected growth rate of 11% from 2018 to 2028. You can find job opportunities in a variety of settings, including hospitals, clinics, research labs, and government agencies. Notable employers include Mayo Clinic, Quest Diagnostics, and the Centers for Disease Control and Prevention. So if you're interested in a career that combines science, technology, and healthcare, consider exploring the world of Medical Laboratory Science. Who knows - you could be the next person to discover a life-saving breakthrough!

The human body is made up of trillions of cells, with each cell originating deep within our bones. The porous nature of bones allows for large and small blood vessels to enter, with the hollow core of most bones containing soft bone marrow. This marrow is essential, containing blood stem cells that constantly divide and differentiate into red and white blood cells and platelets, sending billions of new blood cells into circulation every day. Blood cancers often begin with genetic mutations in these stem cells, which can result in malignant blood cells. For patients with advanced blood cancers, the best chance for a cure is often an allogeneic bone marrow transplant. This procedure involves extracting blood stem cells from a donor and infusing them into the patient's body, leading to the regeneration of healthy blood cells. While bone marrow transplants come with risks, including graft-versus-host disease, it is crucial to find the best match possible for the recipient. Donor registries offer hope to those without a matched family member. Learning about the importance of bone marrow and stem cells can inspire students to explore the fascinating world of human biology and potentially make a difference in someone's life through donation.

Singapore's national flower, Papilionanthe Miss Joaquim, has had its entire genetic blueprint decoded, revealing natural products with antioxidant properties and distinctive colors. The study, published in Communications Biology, could lead to future research in gene and metabolite engineering, as well as the discovery of bioactive compounds for healthcare purposes. The collaboration between A\*STAR's Genome Institute of Singapore and SingHealth Duke-NUS Institute of Biodiversity Medicine showcases the power of genetic sequencing technology in preserving and studying Singapore's plant biodiversity.

Did you know that low concentrations of chloride can produce a sweet taste sensation? Scientists from Okayama University in Japan have discovered a new mechanism for detecting chloride ions in taste buds, shedding light on how we perceive taste. Using mice models and structural biology methods, they found that chloride ions activate sweet receptors, similar to other taste substances. This study could lead to a better understanding of taste perception in organisms.

Researchers have identified lipid differences in patients with alcohol-related liver disease that could lead to earlier detection and new treatments. Sphingomyelins were found to be significantly reduced in scarred liver tissue, potentially serving as a biomarker for ALD. Learn more about this breakthrough research and its implications for the diagnosis and treatment of ALD.

Cells are the fundamental units of life, driven by the forces of the universe, and are impossible machines. They are biological robots that follow their programming, which has evolved over billions of years. Your cells are mostly filled with water molecules and proteins, which are the dead things that make life happen. Cells speak the language of life, which is made up of proteins that are formed from amino acids. Amino acids are the alphabet of the language of life, and proteins are the words that form sentences called biological pathways. The language of life is complex, and mindless cells speak it through DNA, which contains instructions, genes, and building manuals for all the proteins your cells need to function. Understanding the language of life can help you appreciate the amazing complexity of cells and their role in keeping you alive.