The world of science is constantly evolving, and with it comes new discoveries that can benefit humanity. However, there are also risks associated with scientific research, particularly in the field of biotechnology. Gain of function work involves manipulating the DNA of microorganisms to give them new abilities, which can be used in vaccine production and cancer treatments. However, this work also includes engineering superbugs that could cause a global pandemic if they escape from the lab. While virologists argue that this research could help us prepare for future pandemics, critics believe that the risks outweigh the benefits. To minimize the risk of lab leaks, experts suggest creating international databases of leaks, near-misses, and fixes, as well as developing a robust pandemic early warning system. As students, it is important to understand the benefits and risks of scientific research and to be aware of the measures being taken to minimize the risks associated with it.

An interdisciplinary UCLA research team has developed a tiny implantable device called SymphNode, which has been shown to be able to drive tumours into remission, eliminate metastasis, and prevent the growth of new tumours, resulting in longer survival in mice. This groundbreaking technology may decrease the risk of cancer returning, making it a potential addition to chemotherapy or other first-step treatments for a variety of cancers.

Singapore's national flower, Papilionanthe Miss Joaquim, has had its entire genetic blueprint decoded, revealing natural products with antioxidant properties and distinctive colors. The study, published in Communications Biology, could lead to future research in gene and metabolite engineering, as well as the discovery of bioactive compounds for healthcare purposes. The collaboration between A\*STAR's Genome Institute of Singapore and SingHealth Duke-NUS Institute of Biodiversity Medicine showcases the power of genetic sequencing technology in preserving and studying Singapore's plant biodiversity.

The human body is made up of trillions of cells, with each cell originating deep within our bones. The porous nature of bones allows for large and small blood vessels to enter, with the hollow core of most bones containing soft bone marrow. This marrow is essential, containing blood stem cells that constantly divide and differentiate into red and white blood cells and platelets, sending billions of new blood cells into circulation every day. Blood cancers often begin with genetic mutations in these stem cells, which can result in malignant blood cells. For patients with advanced blood cancers, the best chance for a cure is often an allogeneic bone marrow transplant. This procedure involves extracting blood stem cells from a donor and infusing them into the patient's body, leading to the regeneration of healthy blood cells. While bone marrow transplants come with risks, including graft-versus-host disease, it is crucial to find the best match possible for the recipient. Donor registries offer hope to those without a matched family member. Learning about the importance of bone marrow and stem cells can inspire students to explore the fascinating world of human biology and potentially make a difference in someone's life through donation.

Have you ever wondered why a black eye turns blue, then green, then yellow, and finally brown before disappearing? It's all because of your hemoglobin, the compound in red blood cells that brings oxygen to your body. When you get hit, the blow crushes tiny blood vessels called capillaries, and red blood cells ooze out of the broken capillaries into the surrounding tissue. From the outside of your skin, this mass of cells looks bluish-black, which is where we get the term, "black and blue". Learning about hemoglobin and how it works in your body can be fascinating and practical knowledge that can help you understand how your body works. It's an example of how exploring academic topics through reading, reflection, and writing can inspire you to learn more about the world around you.

Are you curious about the tiny viruses that inhabit your body? MIT Technology Review's biotech newsletter, The Checkup, explores the world of bacteriophages, or "phages" for short. These microscopic viruses have the potential to treat bacterial infections, but they've been largely abandoned in favor of antibiotics. With antimicrobial resistance on the rise, interest in phage therapy is making a comeback. Learn about the diversity and specificity of phages, and how they could be engineered to target specific bacteria. Discover the potential of phage therapy and the challenges that need to be overcome in this fascinating article.

Mitochondria are often referred to as the powerhouses of the cell and for good reason. These tiny organelles are responsible for producing the energy that our cells need to function. In this write-up, we'll explore the magic of mitochondria and why they are so important to our health and well-being. Did you know that mitochondria are sometimes referred to as the "second genome"? This is because they have their own DNA and can replicate independently of the cell's nucleus. This discovery, made by Dr. Douglas C. Wallace in the late 1970s, revolutionized our understanding of cellular biology. Another interesting fact about mitochondria is that they are thought to have originated from a symbiotic relationship between early cells and primitive bacteria. Over time, the two organisms evolved together to form the cells that make up our bodies today. This theory, known as the endosymbiotic theory, was first proposed by Dr. Lynn Margulis in the 1960s. So, what exactly do mitochondria do? Well, they are responsible for producing energy in the form of ATP (adenosine triphosphate) through a process called cellular respiration. This energy is then used by our cells to carry out all of their functions, from moving and growing, to repairing and reproducing. It's important to note that our cells can't survive without energy, and without mitochondria, we wouldn't be able to produce enough energy to support our bodies. This is why mitochondria are so critical to our health and well-being. By learning more about the magic of mitochondria, you'll gain a deeper understanding of cellular biology and the role that these tiny organelles play in our lives. So, get reading, reflecting, and exploring!

Horseshoe crabs, a resilient species that has existed for over 450 million years, are facing heightened pressures due to the booming global demand for their blue blood. This blood is the only known natural source of amebocyte lysate, a clotting agent used to detect dangerous endotoxins in a variety of human medical products, including COVID vaccines. The Atlantic horseshoe crab, already considered vulnerable by conservation groups, is facing dwindling numbers due to increased bleedings by biomedical companies. As the industry shifts towards the Atlantic species, questions arise about our obligations to the animals that supply life-saving materials for human benefit.

Ballet dancers can perform pirouettes without feeling dizzy. Researchers found that years of training enable dancers to suppress signals from the balance organs in the inner ear. This discovery could help improve treatment for patients with chronic dizziness. The study also revealed differences in brain structure between dancers and non-dancers. Discover the secrets of dancers' brains and how it could lead to better treatment for chronic dizziness.

Silphion, a golden-flowered plant once prized by the Greeks and Romans for its medicinal and culinary uses, disappeared from the ancient world. But a professor in Turkey may have rediscovered the last holdouts of the plant, which was once valued as highly as gold. Ferula drudeana, a plant with similar characteristics, may be the modern-day version of silphion, with potential for medical breakthroughs. Explore the fascinating story of a plant that was the first recorded extinction and the search for its rediscovery.

The world is still facing daily COVID-19 infections and the threat of virus mutation, but it's not too late to change the game. A pandemic vaccine alliance, similar to NATO, could be the solution to overcome the "free-rider problem" in global health efforts and ensure the world's biological security.

Stanford University researchers, in collaboration with other institutions, have developed a molecule that prevents the spike protein of the SARS-CoV-2 virus from twisting and infecting cells, including those with new variants. This new type of antiviral therapeutic, called the longHR2\_42 inhibitor, may be delivered via inhaler to treat early infections and prevent severe illness. The team's detailed understanding of the twisted structure of the virus's spike protein allowed them to create a longer molecule that is more effective than previous attempts to block the virus. Their groundbreaking research may lead to a promising solution to combat COVID-19.

Have you ever wondered what happens to your blood after it's drawn at the doctor's office? Or how doctors diagnose illnesses and diseases? Enter the world of Medical Laboratory Science, where the magic happens behind the scenes. As a Medical Laboratory Scientist, your role is crucial in the healthcare industry. You'll use advanced laboratory techniques and equipment to analyze patient samples, such as blood, tissue, and bodily fluids, to help diagnose and treat diseases. You'll work with a team of healthcare professionals, including doctors and nurses, to provide accurate and timely results that inform patient care. But what makes this career so appealing? For starters, it's a constantly evolving field. With new technologies and discoveries, you'll always be learning and adapting to stay at the forefront of your profession. Plus, you'll have the satisfaction of knowing that your work directly impacts patient outcomes and helps save lives. In terms of duties, Medical Laboratory Scientists can specialize in a variety of areas, such as microbiology, hematology, or immunology. You may also work in related fields, such as research or public health. Typical tasks include analyzing samples, interpreting results, and communicating findings to healthcare providers. To become a Medical Laboratory Scientist, you'll need at least a Bachelor's degree in Medical Laboratory Science or a related field. Popular undergraduate programs include Biology, Chemistry, and Medical Technology. You'll also need to complete a clinical rotation and pass a certification exam. Helpful personal attributes for this career include attention to detail, critical thinking skills, and the ability to work well under pressure. You'll also need strong communication skills to effectively communicate with healthcare providers and patients. Job prospects for Medical Laboratory Scientists are strong, with a projected growth rate of 11% from 2018 to 2028. You can find job opportunities in a variety of settings, including hospitals, clinics, research labs, and government agencies. Notable employers include Mayo Clinic, Quest Diagnostics, and the Centers for Disease Control and Prevention. So if you're interested in a career that combines science, technology, and healthcare, consider exploring the world of Medical Laboratory Science. Who knows - you could be the next person to discover a life-saving breakthrough!

Are you stressed about aging and the risks it poses to your health? A new study published in Cell Metabolism offers hope. According to Smithsonian Magazine, researchers found that biological age, which is measured by the state of DNA, can be reversed after a stressor subsides. This means that even if stress increases your biological age and raises the risk of certain diseases, it can be reversed once the stress is gone. The study looked at both mice and humans, and the findings are fascinating. Read the full article to learn more about the study's methodology and results.

Researchers have identified lipid differences in patients with alcohol-related liver disease that could lead to earlier detection and new treatments. Sphingomyelins were found to be significantly reduced in scarred liver tissue, potentially serving as a biomarker for ALD. Learn more about this breakthrough research and its implications for the diagnosis and treatment of ALD.

Do you have a passion for helping others and a fascination with the human eye? If so, a career in optometry could be the perfect fit for you! Optometrists are healthcare professionals who specialize in diagnosing and treating vision problems and eye diseases. They play a vital role in helping people maintain healthy eyes and clear vision. As an optometrist, you'll have the opportunity to work with patients of all ages, from children to seniors. You'll use state-of-the-art technology to examine patients' eyes and diagnose problems such as nearsightedness, farsightedness, and astigmatism. You'll also be able to detect and treat eye diseases such as glaucoma, cataracts, and macular degeneration. One of the most appealing aspects of a career in optometry is the ability to make a real difference in people's lives. Imagine helping a child see clearly for the first time or saving someone's vision by detecting a serious eye disease early on. Optometrists have the power to improve their patients' quality of life in meaningful ways. In addition to traditional optometry, there are many areas of specialization within the field. Some optometrists choose to focus on pediatric optometry, working with children to ensure they have healthy eyes and clear vision. Others specialize in contact lenses, helping patients find the perfect lenses to fit their unique needs. And still others focus on low vision, working with patients who have severe visual impairments to help them navigate the world around them. To become an optometrist, you'll need to complete a Doctor of Optometry (OD) degree from an accredited optometry school. Popular undergraduate majors for aspiring optometrists include biology, chemistry, and physics. In addition to completing a rigorous academic program, you'll also need to pass a national board exam to become licensed to practice. Helpful personal attributes for a career in optometry include strong communication skills, attention to detail, and a passion for helping others. You'll also need to be comfortable using technology and working with a wide range of patients. Job prospects for optometrists are strong, with a projected growth rate of 10% over the next decade. Optometrists can work in a variety of settings, from private practices to hospitals to retail stores. Some notable employers in the field include LensCrafters, Kaiser Permanente, and the U.S. Department of Veterans Affairs. So if you're looking for a career that combines cutting-edge technology, meaningful patient interactions, and the opportunity to make a real difference in people's lives, consider a career in optometry!

Cancer is a mysterious and creepy thing, and understanding it is crucial to fighting it. Cancer cells are unstable and selfish, only working for their own short-term benefit. They trick the body into building new blood vessels to feed them, but this can also become their undoing as they continue to mutate. Large animals seem to be immune to cancer, which scientists explain through two main ways: evolution and hypertumors. Evolution means that large animals invest in better cancer defenses, while hypertumors are the tumors of tumors. The solution to the paradox may actually be something different, but researchers still aren't sure what it is. Learning about the nature of cancer cells and cancer defenses can help you understand this complex and important topic.

Frances Oldham Kelsey was a scientist who saved thousands of lives by rejecting an application to sell a drug called thalidomide. The drug was widely used in dozens of countries to treat insomnia, workplace stress, and nausea in pregnant women. However, Kelsey found the data on thalidomide's absorption and toxicity inadequate and rejected the application. Her earlier animal-based research demonstrated that drugs could pass from mother to fetus through the placenta, and she believed that thalidomide could cause harm to fetuses. Her decision to reject the application and ask for better evidence saved countless babies from severe birth defects caused by thalidomide. Kelsey's legacy endures as she prioritized facts over opinions and patience over shortcuts, making evidence-based medicine the foundation of reforms that continue to protect people today. By learning about Kelsey's story, students can understand the importance of evidence-based research and the impact of their decisions in science and medicine.

Learning about the science of breath-holding can be a fascinating and beneficial academic pursuit for high school students. Scientists have discovered that our diaphragm signals our body to take a breath, forcing a breakpoint when holding our breath. With relaxation techniques and distractions, we can delay our personal breakpoint. Learning about the physiology of breath-holding can help us understand our bodies better and develop techniques to improve our lung capacity. Additionally, competitive breath-holders have found that being submerged in water slows their metabolism, allowing them to hold their breath for longer. This academic exploration can improve our physical abilities and mental focus, making it a worthwhile pursuit for high school students.

Ancient Egyptian tombs reveal pots of honey, thousands of years old and still preserved. What makes honey such a special food? The answer lies in its chemical makeup and the alchemy of bees. Honey's longevity and acidic properties lend it medicinal qualities, making it a natural bandage and a barrier against infection for wounds. Discover the magic of honey and its perfect balance of hygroscopic and antimicrobial properties.