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In just a few thousand years, northern Europeans evolved to digest milk, a feat that was once impossible for adult humans. Scientists now believe that exceptional stressors like famines and pathogens may have driven this genetic change, making the ability to digest milk extra valuable. This study, published in Nature and led by experts from the University of Bristol and University College London, sheds light on the evolution of lactose tolerance and rewrites the textbooks on why drinking milk was an advantage.
Are you curious about the secrets hidden in ancient DNA? Harvard University has made a groundbreaking discovery that could change the way we understand life on earth. Scientists have managed to reconstruct the genomes of microorganisms up to 100,000 years old, and even revived molecules from the Stone Age in the lab. The group’s findings and genome-reconstruction techniques are outlined in a paper published in Science. This is an exciting breakthrough that could lead to the discovery of new oral species and biochemicals with therapeutic potential. Don't miss out on this fascinating article!
The discovery of the structure of DNA is one of the most important scientific achievements in human history. While Watson and Crick are often credited with this breakthrough, Rosalind Franklin's scientific contributions have been vastly underplayed. Franklin faced sexism and isolation from her colleagues, but she kept working and obtained Photo 51, the most famous x-ray image of DNA. Her calculations led her to the same conclusion as Watson and Crick, but her manuscript was published last, making it look like her experiments just confirmed their breakthrough instead of inspiring it. Franklin's work revolutionized medicine, biology, and agriculture. Learning about her story will not only provide insight into the history of science but also inspire students to pursue their passions regardless of societal barriers.
Science is not always confined to laboratories with white coats and high-tech gadgets. The Weird History of the Cell Theory shows how even the most groundbreaking discoveries can have strange and varied beginnings. The discovery of cells and the development of the cell theory started with Zacharias Janssen's invention of the microscope in the early 1600s. Anton van Leeuwenhoek, a Dutchman, discovered bacteria by looking at dental scrapings through his homemade microscope. Robert Hooke, another scientist, coined the term "the cell" while looking at a piece of cork. Matthias Schleiden and Theodor Schwann discovered that every plant and animal is made of cells. Rudolph Virchow proved that cells come from other cells. Learning about the history of scientific discoveries can be exciting and inspiring, and it shows that anyone can make a significant contribution to science, even with limited resources.
Scientists sequence Beethoven's genome from locks of hair, revealing new insights into his health and ancestry. The study, led by Cambridge University and other institutions, uncovers genetic risk factors for liver disease and an infection with Hepatitis B virus. Beethoven's hearing loss remains a mystery, but his genomic data rules out coeliac disease and lactose intolerance as potential causes. The study sheds light on the composer's health problems, including chronic gastrointestinal complaints and a severe liver disease that likely contributed to his death at age 56.
Tardigrades have even been featured in popular culture, including an episode of Star Trek: Discovery, where they were used as a propulsion system for a spaceship. But while tardigrades may seem like science fiction, they are very much a real and fascinating part of the natural world. These tiny, water-dwelling creatures, also known as water bears or moss piglets, have been around for over half a billion years and have evolved some truly remarkable survival strategies. Tardigrades can survive in extreme environments that would kill most other organisms, including temperatures ranging from -272°C to 151°C, pressures six times greater than those at the bottom of the ocean, and even the vacuum of space. They can also survive dehydration, radiation, and exposure to toxins. Tardigrades achieve this impressive feat through a combination of strategies, including the ability to enter a state of suspended animation called cryptobiosis, which allows them to survive without water for years. One of the key factors that enable tardigrades to survive in such extreme conditions is their ability to repair their DNA. Tardigrades have a unique protein called Dsup, which protects their DNA from damage caused by radiation. This protein has even been shown to protect human cells from radiation damage. Dr. Thomas Boothby, a leading tardigrade researcher at the University of Wyoming, has discovered that tardigrades can also produce large amounts of unique proteins called tardigrade-specific intrinsically disordered proteins (TDPs) in response to desiccation. These proteins help protect the tardigrades' cells from damage and prevent them from drying out. Tardigrades are fascinating not just for their survival abilities, but also for their unique biology. They have a complex digestive system, a unique nervous system, and a fascinating reproductive system that involves the transfer of genetic material between individuals. By exploring the science behind these tiny creatures, we can gain a deeper understanding of the natural world and the amazing ways that living organisms can survive and thrive in even the most extreme conditions.
The past is a vast and mysterious land that holds the key to understanding our present. Learning about creatures of the past requires fossils, remains preserved from past geological ages. The totality of all fossils on earth is called the fossil record, and it is the most important window on the past we'll ever have. For a dead animal to fossilize, a number of things must go just right. It's kind of a miracle that we have what we have and know what we know. We've entered a golden era of discovery, and about 50 new dinosaur species are discovered each year, expanding what we know and what we know that we don't know about them, which is amazing. Although many species are lost forever, fossils of mostly soft and gooey species also left us an incredible diversity of shells that tell us an amazing amount about our past. Learning about the past is not only intellectually stimulating, but it also helps us understand the world around us today.
Our ears are as unique as our fingerprints, and they serve a crucial role in our lives. They help us communicate with others, recognize complex emotions, and locate sounds. Even before we are born, our ears are already listening, and after we are born, they become even more useful. The inner workings of the ear heighten the frequencies of the human voice, making listening a more effective way to recognize and decode complex human emotions than looking at facial expressions. Our external ears may not serve us well on a hot day, but they can be an indicator of our health. Moreover, the shape and folds of our ears, and how the brain processes sound waves, help us determine where a sound is coming from. Learning about the fascinating workings of our ears can help us appreciate their importance and how they benefit us intellectually and practically.
Ever heard of umami? It's the mystery taste that adds savouriness to your favorite foods and has been recognized as a basic taste along with sweet, sour, bitter, and salt. Join the Japanese chemist Kikunae Ikeda on his journey of isolating the key amino acid responsible for the taste and revolutionizing the food industry with his discovery.
Singapore's national flower, Papilionanthe Miss Joaquim, has had its entire genetic blueprint decoded, revealing natural products with antioxidant properties and distinctive colors. The study, published in Communications Biology, could lead to future research in gene and metabolite engineering, as well as the discovery of bioactive compounds for healthcare purposes. The collaboration between A\*STAR's Genome Institute of Singapore and SingHealth Duke-NUS Institute of Biodiversity Medicine showcases the power of genetic sequencing technology in preserving and studying Singapore's plant biodiversity.
Have you ever imagined walking alongside a giant, hairy elephant with long tusks and a hump of fat on its back? Meet the woolly mammoth, an extinct species that lived during the Ice Ages. As you learn about the woolly mammoth, you will discover fascinating features such as their two-layered fur and impressive size, which was larger than modern elephants. More than just a fun fact, studying extinct animals like the woolly mammoth can help us understand how Earth's climate and environment have changed over time, and how humans have influenced the planet. By exploring these academic concepts through reading, reflection, writing and self-directed projects, you can develop your intellectual curiosity and creativity while also gaining practical skills in research, critical thinking, and communication.
DNA is a molecule that holds the secrets of life within its code, and it's waiting for you to explore it! This amazing molecule determines our traits, from our physical appearance to our personalities, and it can also tell us about our ancestry, our risk of diseases, and much more. Leading academics in the field of genetics, such as James Watson and Francis Crick, made major contributions to our understanding of DNA by discovering its structure and how it stores and transfers genetic information. Watson and Crick's discovery of the double helix structure of DNA was a major turning point in the field of genetics and opened up new avenues for scientific research. In the early 1990s, the Human Genome Project was launched to map all of the genes in human DNA. This project was a huge success and has had a profound impact on the field of genetics. It allowed scientists to identify specific genes that are associated with different diseases, such as cancer, and has paved the way for new treatments and cures. One of the most fascinating things about DNA is that every person's DNA is 99.9% identical to every other person's DNA. It's the remaining 0.1% that makes each of us unique! Our DNA also contains fascinating stories about our ancestors and their migrations. For example, DNA testing can tell us where our ancestors came from and how they migrated across the world. This is known as genetic genealogy, and it's an exciting field that combines genetics and history. Another fascinating aspect of DNA is its role in evolution. Charles Darwin's theory of evolution by natural selection states that species change over time through the process of natural selection. This process occurs because certain traits that provide an advantage in survival and reproduction become more common in a population over time. DNA mutations can lead to changes in traits, and over many generations, these changes can accumulate and result in new species. By exploring the world of DNA, you will not only deepen your understanding of genetics and biology, but also gain a new appreciation for the complexities and wonders of life. So go ahead, unlock the secrets of life with the power of DNA!
Cells are the fundamental units of life, driven by the forces of the universe, and are impossible machines. They are biological robots that follow their programming, which has evolved over billions of years. Your cells are mostly filled with water molecules and proteins, which are the dead things that make life happen. Cells speak the language of life, which is made up of proteins that are formed from amino acids. Amino acids are the alphabet of the language of life, and proteins are the words that form sentences called biological pathways. The language of life is complex, and mindless cells speak it through DNA, which contains instructions, genes, and building manuals for all the proteins your cells need to function. Understanding the language of life can help you appreciate the amazing complexity of cells and their role in keeping you alive.
Did you know that low concentrations of chloride can produce a sweet taste sensation? Scientists from Okayama University in Japan have discovered a new mechanism for detecting chloride ions in taste buds, shedding light on how we perceive taste. Using mice models and structural biology methods, they found that chloride ions activate sweet receptors, similar to other taste substances. This study could lead to a better understanding of taste perception in organisms.
Your food preferences may be coded in your DNA. Discover how genetics and exposure shape our taste buds and why some people are supertasters. Learn how food likes and dislikes are influenced by nature and nurture. Explore the science of flavor perception and the role of TAS2R38 gene.
Silphion, a golden-flowered plant once prized by the Greeks and Romans for its medicinal and culinary uses, disappeared from the ancient world. But a professor in Turkey may have rediscovered the last holdouts of the plant, which was once valued as highly as gold. Ferula drudeana, a plant with similar characteristics, may be the modern-day version of silphion, with potential for medical breakthroughs. Explore the fascinating story of a plant that was the first recorded extinction and the search for its rediscovery.
Do you ever wonder why orange juice tastes so bad after brushing your teeth? It turns out that our taste buds, which are made up of taste receptor cells, are responsible for identifying different tastes like sweet, bitter, and savory. Toothpaste contains Sodium Lauryl Sulphate (SLS), which creates foam while brushing and temporarily gets rid of the molecules that block our bitter receptors. This makes the receptor much more sensitive to bitter flavors, causing that awful taste. However, taste isn't just affected by our receptors. Temperature, texture, and smell can change what we sense too. Learning about the science of taste can help you understand why some foods taste the way they do and how to enhance your dining experience. So, next time you have OJ after brushing, try plugging your nose or go for a coffee or Bloody Mary instead.
Learning about the chemistry of onions may not seem like the most exciting academic topic, but it can help you understand how things work in the world around you. When you chop an onion, you're changing its chemistry and releasing a gas that causes your eyes to water. You can slow down the onion's enzymes by storing it in the fridge or boiling it briefly, or you can wear goggles or sunglasses while cutting it. Scientists are even working on creating tear-free onions through genetic modification and traditional plant breeding. Learning about the chemistry of onions can help you appreciate the complexities of the natural world and give you practical skills for your everyday life.
How do we grow seedless fruit? Discover the fascinating history and science behind hybridization and grafting, and the latest genetic research that could lead to new seedless varieties. From Navel oranges to mutant sugar apples, explore the world of fruit breeding.
Can a single cell's physical properties predict how tall a tree can grow? MIT Professor Ming Guo's research in cell mechanics reveals how a cell's physical form can influence the growth of an entire organism, including disease such as cancer. With his interdisciplinary work in physics, mechanical engineering, and cell biology, Guo aims to engineer materials for biomedical applications.
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